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Influence of marital status on the survival of adults with extrahepatic/intrahepatic cholangiocarcinoma

Although the prognostic value of marital status has been implicated in many cancers, its prognostic impact on cholangiocarcinoma has not yet been determined. The aim of this study was to examine the association between marital status and cholangiocarcinoma survival. We included 8,776 extrahepatic ch...

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Autores principales: Chen, Zhiqiang, Pu, Liyong, Gao, Wen, Zhang, Long, Han, Guoyong, Zhu, Qin, Li, Xiangcheng, Wu, Jindao, Wang, Xuehao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438705/
https://www.ncbi.nlm.nih.gov/pubmed/28415824
http://dx.doi.org/10.18632/oncotarget.16330
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author Chen, Zhiqiang
Pu, Liyong
Gao, Wen
Zhang, Long
Han, Guoyong
Zhu, Qin
Li, Xiangcheng
Wu, Jindao
Wang, Xuehao
author_facet Chen, Zhiqiang
Pu, Liyong
Gao, Wen
Zhang, Long
Han, Guoyong
Zhu, Qin
Li, Xiangcheng
Wu, Jindao
Wang, Xuehao
author_sort Chen, Zhiqiang
collection PubMed
description Although the prognostic value of marital status has been implicated in many cancers, its prognostic impact on cholangiocarcinoma has not yet been determined. The aim of this study was to examine the association between marital status and cholangiocarcinoma survival. We included 8,776 extrahepatic cholangiocarcinoma cases and 1,352 intrahepatic cholangiocarcinoma cases between 1973 and 2013 from the Surveillance, Epidemiology, and End Results database. We found widowed patients were more likely to be female, aged more than 70, and from low income areas. Multivariate analysis indicated that marital status was an independent prognostic factor for extrahepatic cholangiocarcinoma patients. Subgroup analysis suggested the widowed status independently predicted poor survival at regional stage and in older patients with intrahepatic cholangiocarcinoma. To conclude, marital status is a valuable prognostic factor in cholangiocarcinoma, and widowed patients are at greater risk of death than others.
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spelling pubmed-54387052017-05-24 Influence of marital status on the survival of adults with extrahepatic/intrahepatic cholangiocarcinoma Chen, Zhiqiang Pu, Liyong Gao, Wen Zhang, Long Han, Guoyong Zhu, Qin Li, Xiangcheng Wu, Jindao Wang, Xuehao Oncotarget Research Paper Although the prognostic value of marital status has been implicated in many cancers, its prognostic impact on cholangiocarcinoma has not yet been determined. The aim of this study was to examine the association between marital status and cholangiocarcinoma survival. We included 8,776 extrahepatic cholangiocarcinoma cases and 1,352 intrahepatic cholangiocarcinoma cases between 1973 and 2013 from the Surveillance, Epidemiology, and End Results database. We found widowed patients were more likely to be female, aged more than 70, and from low income areas. Multivariate analysis indicated that marital status was an independent prognostic factor for extrahepatic cholangiocarcinoma patients. Subgroup analysis suggested the widowed status independently predicted poor survival at regional stage and in older patients with intrahepatic cholangiocarcinoma. To conclude, marital status is a valuable prognostic factor in cholangiocarcinoma, and widowed patients are at greater risk of death than others. Impact Journals LLC 2017-03-17 /pmc/articles/PMC5438705/ /pubmed/28415824 http://dx.doi.org/10.18632/oncotarget.16330 Text en Copyright: © 2017 Chen et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) (CC-BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Paper
Chen, Zhiqiang
Pu, Liyong
Gao, Wen
Zhang, Long
Han, Guoyong
Zhu, Qin
Li, Xiangcheng
Wu, Jindao
Wang, Xuehao
Influence of marital status on the survival of adults with extrahepatic/intrahepatic cholangiocarcinoma
title Influence of marital status on the survival of adults with extrahepatic/intrahepatic cholangiocarcinoma
title_full Influence of marital status on the survival of adults with extrahepatic/intrahepatic cholangiocarcinoma
title_fullStr Influence of marital status on the survival of adults with extrahepatic/intrahepatic cholangiocarcinoma
title_full_unstemmed Influence of marital status on the survival of adults with extrahepatic/intrahepatic cholangiocarcinoma
title_short Influence of marital status on the survival of adults with extrahepatic/intrahepatic cholangiocarcinoma
title_sort influence of marital status on the survival of adults with extrahepatic/intrahepatic cholangiocarcinoma
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438705/
https://www.ncbi.nlm.nih.gov/pubmed/28415824
http://dx.doi.org/10.18632/oncotarget.16330
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