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Phospholipase Cδ1 suppresses cell migration and invasion of breast cancer cells by modulating KIF3A-mediated ERK1/2/β- catenin/MMP7 signalling

Phospholipase C δ1 (PLCD1) encodes an enzyme involved in energy metabolism, calcium homeostasis and intracellular movement. It is located at 3p22 in a region that is frequently deleted in multiple cancers, and the PLCD1 enzyme is a potential tumour suppressor in breast cancer that inhibits matrix me...

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Detalles Bibliográficos
Autores principales:	Shao, Qing, Luo, Xinrong, Yang, Dejuan, Wang, Can, Cheng, Qiao, Xiang, Tingxiu, Ren, Guosheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438712/ https://www.ncbi.nlm.nih.gov/pubmed/28423710 http://dx.doi.org/10.18632/oncotarget.16072

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