Cargando…

Bone marrow-derived mesenchymal stem cells overexpressing miR-21 efficiently repair myocardial damage in rats

OBJECTIVE: We investigated the ability of bone marrow derived mesenchymal stem cells (BMSCs) overexpressing microRNA-21 (miR-21) to repair cardiac damage induced by anthracyclines in rats. METHODS: Sprague-Dawley (SD) rats of 2~3 weeks old were selected to isolate and culture BMSCs. A lentivirus har...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zeng, Yan-Ling, Zheng, Hao, Chen, Qiu-Ru, Yuan, Xiao-Hong, Ren, Jin-Hua, Luo, Xiao-Feng, Chen, Ping, Lin, Zhe-Yao, Chen, Shao-Zhen, Wu, Xue-Qiong, Xiao, Min, Chen, Yong-Quan, Chen, Zhi-Zhe, Hu, Jian-Da, Yang, Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438721/ https://www.ncbi.nlm.nih.gov/pubmed/28418864 http://dx.doi.org/10.18632/oncotarget.16254

Ejemplares similares

TMSB4 Overexpression Enhances the Potency of Marrow Mesenchymal Stromal Cells for Myocardial Repair
por: Tang, Shiyuan, et al.
Publicado: (2021)

Myocardial Injection of Apelin-Overexpressing Bone Marrow Cells Improves Cardiac Repair via Upregulation of Sirt3 after Myocardial Infarction
por: Li, Lanfang, et al.
Publicado: (2013)

miR-206 inhibits osteogenic differentiation of bone marrow mesenchymal stem cells by targetting glutaminase
por: Chen, Ying, et al.
Publicado: (2019)

Exosomes derived from mir-214-3p overexpressing mesenchymal stem cells promote myocardial repair
por: Zhu, Wenwu, et al.
Publicado: (2023)

PTPN21 Overexpression Promotes Osteogenic and Adipogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells but Inhibits the Immunosuppressive Function
por: Wang, Huafang, et al.
Publicado: (2019)

Repair mechanisms of bone marrow mesenchymal stem cells in myocardial infarction
por: Wen, Zhuzhi, et al.
Publicado: (2011)

MiR-21-5p-expressing bone marrow mesenchymal stem cells alleviate myocardial ischemia/reperfusion injury by regulating the circRNA_0031672/miR-21-5p/programmed cell death protein 4 pathway
por: ZHANG, Jing, et al.
Publicado: (2021)

mir-21 Overexpressing Mesenchymal Stem Cells Accelerate Fracture Healing in a Rat Closed Femur Fracture Model
por: Sun, Yuxin, et al.
Publicado: (2015)

The enhanced effect and underlying mechanisms of mesenchymal stem cells with IL-33 overexpression on myocardial infarction
por: Chen, Yueqiu, et al.
Publicado: (2019)

Editorial: Differentiation and Regulation of Bone Marrow Mesenchymal Stromal Cells
por: Zhang, Hao, et al.
Publicado: (2022)

MicroRNA-133 overexpression promotes the therapeutic efficacy of mesenchymal stem cells on acute myocardial infarction
por: Chen, Yueqiu, et al.
Publicado: (2017)

Microbiota regulates bone marrow mesenchymal stem cell lineage differentiation and immunomodulation
por: Xiao, E, et al.
Publicado: (2017)

miR-199a Overexpression Enhances the Potency of Human Induced-Pluripotent Stem-Cell–Derived Cardiomyocytes for Myocardial Repair
por: Bian, Weihua, et al.
Publicado: (2021)

Overexpression of microRNA-124 promotes the neuronal differentiation of bone marrow-derived mesenchymal stem cells
por: Zou, Defeng, et al.
Publicado: (2014)

SERPINB1 overexpression protects myocardial damage induced by acute myocardial infarction through AMPK/mTOR pathway
por: Wang, Hongliang, et al.
Publicado: (2022)

MiR-21 nanocapsules promote early bone repair of osteoporotic fractures by stimulating the osteogenic differentiation of bone marrow mesenchymal stem cells
por: Sun, Xiaolei, et al.
Publicado: (2020)

660 nm red light-enhanced bone marrow mesenchymal stem cell transplantation for hypoxic-ischemic brain damage treatment
por: Li, Xianchao, et al.
Publicado: (2014)

Exosomes derived from miR‐375‐overexpressing human adipose mesenchymal stem cells promote bone regeneration
por: Chen, Si, et al.
Publicado: (2019)

Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells
por: Chen, Shuwen, et al.
Publicado: (2020)

H19 Overexpression Improved Efficacy of Mesenchymal Stem Cells in Ulcerative Colitis by Modulating the miR-141/ICAM-1 and miR-139/CXCR4 Axes
por: Zhao, Ming-li, et al.
Publicado: (2021)

SOD2 overexpression in bone marrow-derived mesenchymal stem cells ameliorates hepatic ischemia/reperfusion injury
por: Li, Qiuyun, et al.
Publicado: (2021)

Nuclear Transglutaminase 2 interacts with topoisomerase II⍺ to promote DNA damage repair in lung cancer cells
por: Lei, Xiao, et al.
Publicado: (2021)

Mesenchymal stem cells overexpressing Ihh promote bone repair
por: Zou, Shasha, et al.
Publicado: (2014)

Hypomethylation Causes MIR21 Overexpression in Tumors
por: Lu, Jun, et al.
Publicado: (2020)

MKP-1 Overexpression Reduces Postischemic Myocardial Damage through Attenuation of ER Stress and Mitochondrial Damage
por: Hou, Xiaoling, et al.
Publicado: (2021)

Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial–mesenchymal transition in gastric cancer
por: He, Xiaobo, et al.
Publicado: (2022)

Propofol promotes spinal cord injury repair by bone marrow mesenchymal stem cell transplantation
por: Zhou, Ya-jing, et al.
Publicado: (2015)

The Application of a Bone Marrow Mesenchymal Stem Cell Membrane in the Vascularization of a Decellularized Tracheal Scaffold
por: Yao, Zhi-Ye, et al.
Publicado: (2021)

Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM
por: Xu, Shihao, et al.
Publicado: (2022)

Characterization of bone marrow derived mesenchymal stem cells in suspension
por: Akiyama, Kentaro, et al.
Publicado: (2012)

miR-21 Overexpression Promotes Esophageal Squamous Cell Carcinoma Invasion and Migration by Repressing Tropomyosin 1
por: Shen, Zhuojian, et al.
Publicado: (2020)

Exosomes Isolated From Bone Marrow Mesenchymal Stem Cells Exert a Protective Effect on Osteoarthritis via lncRNA LYRM4-AS1-GRPR-miR-6515-5p
por: Wang, Xiuhui, et al.
Publicado: (2021)

Overexpression of miR-106a enhances oxaliplatin sensitivity of colorectal cancer through regulation of FOXQ1
por: Liu, Zhihu, et al.
Publicado: (2020)

The interaction of miR-181a-5p and sirtuin 1 regulated human bone marrow mesenchymal stem cells differentiation and apoptosis
por: Zhu, Haitao, et al.
Publicado: (2021)

Overexpression of Insulin-Like Growth Factor 1 Enhanced the Osteogenic Capability of Aging Bone Marrow Mesenchymal Stem Cells
por: Chen, Ching-Yun, et al.
Publicado: (2017)

Overexpression of miR-150-5p Alleviates Apoptosis in Sepsis-Induced Myocardial Depression
por: Zhu, Xiao Geng, et al.
Publicado: (2020)

Overexpression of c-Met in bone marrow mesenchymal stem cells improves their effectiveness in homing and repair of acute liver failure
por: Wang, Kun, et al.
Publicado: (2017)

RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation
por: Chen, Xiao, et al.
Publicado: (2018)

Bone marrow-derived mesenchymal stem cell transplantation attenuates overexpression of inflammatory mediators in rat brain after cardiopulmonary resuscitation
por: Lin, Qing-Ming, et al.
Publicado: (2019)

HIF-1α overexpression in mesenchymal stem cell-derived exosomes mediates cardioprotection in myocardial infarction by enhanced angiogenesis
por: Sun, Jiacheng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8dd2qnn3e4hr7i4sht7frsvsiv