Kinomic profiling identifies focal adhesion kinase 1 as a therapeutic target in advanced clear cell renal cell carcinoma

The introduction of targeted therapies has caused a paradigm shift in the treatment of metastatic clear cell (cc)-renal cell carcinoma (RCC). We hypothesized that determining differential kinase activity between primary and metastatic tumor sites may identify critical drivers of progression and rele...

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Detalles Bibliográficos
Autores principales: Ghosh, Arindam P., Willey, Christopher D., Anderson, Joshua C., Welaya, Karim, Chen, Dongquan, Mehta, Amitkumar, Ghatalia, Pooja, Madan, Ankit, Naik, Gurudatta, Sudarshan, Sunil, Sonpavde, Guru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438725/
https://www.ncbi.nlm.nih.gov/pubmed/28418903
http://dx.doi.org/10.18632/oncotarget.16352

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