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GYF-21, an Epoxide 2-(2-Phenethyl)-Chromone Derivative, Suppresses Innate and Adaptive Immunity via Inhibiting STAT1/3 and NF-κB Signaling Pathways

Multiple sclerosis is a chronic inflammatory autoimmune disease of the central nervous system characterized by demyelinating plaques and axonal loss. Inhibition on over activation of innate and adaptive immunity provides a rationale strategy for treatment of multiple sclerosis. In the present study,...

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Detalles Bibliográficos
Autores principales: Guo, Ran, Zhao, Yun-Fang, Li, Jun, Gu, Yu-Fan, Huo, Hui-Xia, Li, Shan-Shan, Song, Yue-Lin, Zhu, Zhi-Xiang, Tu, Peng-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438969/
https://www.ncbi.nlm.nih.gov/pubmed/28588487
http://dx.doi.org/10.3389/fphar.2017.00281