Cargando…

Calreticulin in Essential Thrombocythemia: StressINg OUT the Megakaryocyte Nucleus

Calreticulin (CALR) is a multifaceted protein primarily involved in intracellular protein control processes. The identification of CALR mutations in essential thrombocythemia (ET) and primary myelofibrosis that are mutually exclusive with the JAK2 V617F mutation has stirred an intensive research int...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iborra, Francisco Jose, Papadopoulos, Petros
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438987/ https://www.ncbi.nlm.nih.gov/pubmed/28589084 http://dx.doi.org/10.3389/fonc.2017.00103

Ejemplares similares

Mutant calreticulin causes essential thrombocythemia
por: Shimoda, Kazuya, et al.
Publicado: (2017)

Alterations of Signaling Pathways in Essential Thrombocythemia with Calreticulin Mutation
por: Hui, Wuhan, et al.
Publicado: (2021)

Calreticulin Mutated Essential Thrombocythemia Presenting as Acute Coronary Syndrome
por: Nazha, Bassel, et al.
Publicado: (2015)

Two Novel Monoallelic Calreticulin Mutations in a Patient With Essential Thrombocythemia
por: Kamory, Eniko, et al.
Publicado: (2017)

Structural and Dynamic Differences between Calreticulin Mutants Associated with Essential Thrombocythemia
por: Radjasandirane, Ragousandirane, et al.
Publicado: (2023)

Calreticulin mutant mice develop essential thrombocythemia that is ameliorated by the JAK inhibitor ruxolitinib
por: Shide, K, et al.
Publicado: (2017)

Comparison of Clinical and Hematological Parameters of Janus Kinase 2, Calreticulin or Myeloproliferative Leukemia Virus Oncogene Mutant Essential Thrombocythemia and Triple-Negative Essential Thrombocythemia
por: Yıldız, Jale, et al.
Publicado: (2022)

Essential thrombocythemia with (type2) calreticulin presented as stuttering priapism case report and review of literature
por: Ali, Elrazi Awadelkarim, et al.
Publicado: (2020)

Hematological relevance of JAK2 V617F and calreticulin mutations in Tunisian patients with essential thrombocythemia
por: Abdelghani, Maroua, et al.
Publicado: (2022)

The stem/progenitor landscape is reshaped in a mouse model of essential thrombocythemia and causes excess megakaryocyte production
por: Prins, Daniel, et al.
Publicado: (2020)

Myocardial Infarction as an Initial Presentation of Essential Thrombocythemia With Calreticulin (CALR) Mutation (None Type 1, None Type 2)
por: Afana, Mohammad, et al.
Publicado: (2023)

Essential thrombocythemia
por: Brière, Jean B
Publicado: (2007)

Thrombophilic Risk of Factor V Leiden, Prothrombin G20210A, MTHFR, and Calreticulin Mutations in Essential Thrombocythemia Egyptian Patients
por: El-Ghonemy, Mohamed S., et al.
Publicado: (2020)

Rebound of platelet count in a patient with type 2 calreticulin-mutant essential thrombocythemia in the postpartum period: A case report
por: Al-Mashdali, Abdulrahman F., et al.
Publicado: (2021)

The molecular profile in patients with polycythemia vera and essential thrombocythemia is dynamic and correlates with disease’s phenotype
por: Sobieralski, Patryk, et al.
Publicado: (2023)

Evaluation of Therapeutic Strategies to Reduce the Number of Thrombotic Events in Patients With Polycythemia Vera and Essential Thrombocythemia
por: Tremblay, Douglas, et al.
Publicado: (2021)

Pegylated Interferon Alpha-2b in Patients With Polycythemia Vera and Essential Thrombocythemia in the Real World
por: Sun, Yingxin, et al.
Publicado: (2021)

Ruxolitinib for essential thrombocythemia?
por: Bose, Prithviraj, et al.
Publicado: (2017)

Genetic Alterations in Essential Thrombocythemia Progression to Acute Myeloid Leukemia: A Case Series and Review of the Literature
por: Ayres-Silva, Jackline P., et al.
Publicado: (2018)

Triple-Negative Essential Thrombocythemia: Clinical-Pathological and Molecular Features. A Single-Center Cohort Study
por: Cattaneo, Daniele, et al.
Publicado: (2021)

Clinical Manifestation of Calreticulin Gene Mutations in Essential Thrombocythemia without Janus Kinase 2 and MPL Mutations: A Chinese Cohort Clinical Study
por: Sun, Chao, et al.
Publicado: (2016)

Calreticulin Is Essential for Cardiac Development
por: Mesaeli, Nasrin, et al.
Publicado: (1999)

Megakaryocytes as the Regulator of the Hematopoietic Vascular Niche
por: Zhan, Huichun, et al.
Publicado: (2022)

Editorial: Megakaryocytes as regulators of tumor microenvironments
por: Migliaccio, Anna Rita, et al.
Publicado: (2022)

The Ever-Expanding Immunomodulatory Role of Calreticulin in Cancer Immunity
por: de Bruyn, Marco, et al.
Publicado: (2015)

Emerging treatments for essential thrombocythemia
por: Okoli, Steven, et al.
Publicado: (2011)

Thromboembolic complication in Essential Thrombocythemia
por: Mozaheb, Zahra
Publicado: (2012)

Essential thrombocythemia: Busulphan revisited
por: Koduri, Prasad R.
Publicado: (2016)

Ruxolitinib for the Treatment of Essential Thrombocythemia
por: Gunawan, Arief, et al.
Publicado: (2018)

Essential Thrombocythemia in Children and Adolescents
por: Putti, Maria Caterina, et al.
Publicado: (2021)

Mutations and thrombosis in essential thrombocythemia
por: Guglielmelli, Paola, et al.
Publicado: (2021)

Case Report: Effects of multiple myeloma therapy on essential thrombocythemia and vice versa: a case of synchronous dual hematological malignancy
por: Krishnan, Nupur, et al.
Publicado: (2023)

Impaired apoptosis of megakaryocytes and bone marrow mononuclear cells in essential thrombocythemia: correlation with JAK2V617F mutational status and cytoreductive therapy
por: Treliński, Jacek, et al.
Publicado: (2012)

Megakaryocyte Diversity in Ontogeny, Functions and Cell-Cell Interactions
por: Khatib-Massalha, Eman, et al.
Publicado: (2022)

Moyamoya syndrome in an adult with essential thrombocythemia
por: Lazzaro, Marc A., et al.
Publicado: (2011)

Essential thrombocythemia: Rare cause of chorea
por: Venkatesan, Eswaradass Prasanna, et al.
Publicado: (2014)

Essential thrombocythemia treatment algorithm 2018
por: Tefferi, Ayalew, et al.
Publicado: (2018)

Essential Thrombocythemia Presenting as Paraneoplastic Glomerulonephritis
por: Abdulla, M. C., et al.
Publicado: (2018)

Calreticulin-mutant proteins induce megakaryocytic signaling to transform hematopoietic cells and undergo accelerated degradation and Golgi-mediated secretion
por: Han, Lijuan, et al.
Publicado: (2016)

Transcriptional Regulation of ING5 and its Suppressive Effects on Gastric Cancer
por: Zheng, Hua-chuan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6crcf5vnrbqrp07f4gng3h8fgm