Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial

BACKGROUND: Hot flushes affect 70% of menopausal women and often severely impact physical, psychosocial, sexual, and overall wellbeing. Hormone replacement therapy is effective but is not without risk. Neurokinin B signalling is increased in menopausal women, and has been implicated as an important...

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Detalles Bibliográficos
Autores principales: Prague, Julia K, Roberts, Rachel E, Comninos, Alexander N, Clarke, Sophie, Jayasena, Channa N, Nash, Zachary, Doyle, Chedie, Papadopoulou, Deborah A, Bloom, Stephen R, Mohideen, Pharis, Panay, Nicholas, Hunter, Myra S, Veldhuis, Johannes D, Webber, Lorraine C, Huson, Les, Dhillo, Waljit S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439024/
https://www.ncbi.nlm.nih.gov/pubmed/28385352
http://dx.doi.org/10.1016/S0140-6736(17)30823-1

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