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Inactive Hepatitis B Carrier and Pregnancy Outcomes: A Systematic Review and Meta–analysis
BACKGROUND: We aimed to explore whether maternal asymptomatic hepatitis B (HB) infection effects on pre-term rupture of membranous (PROM), stillbirth, preeclampsia, eclampsia, gestational hypertension, or antepartum hemorrhage. METHODS: We searched the PubMed, Scopus, and ISI web of science from 199...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439035/ https://www.ncbi.nlm.nih.gov/pubmed/28540262 |
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author | KERAMAT, Afsaneh YOUNESIAN, Masud GHOLAMI FESHARAKI, Mohammad HASANI, Maryam MIRZAEI, Samaneh EBRAHIMI, Elham ALAVIAN, Seyed Moaed MOHAMMADI, Fatemeh |
author_facet | KERAMAT, Afsaneh YOUNESIAN, Masud GHOLAMI FESHARAKI, Mohammad HASANI, Maryam MIRZAEI, Samaneh EBRAHIMI, Elham ALAVIAN, Seyed Moaed MOHAMMADI, Fatemeh |
author_sort | KERAMAT, Afsaneh |
collection | PubMed |
description | BACKGROUND: We aimed to explore whether maternal asymptomatic hepatitis B (HB) infection effects on pre-term rupture of membranous (PROM), stillbirth, preeclampsia, eclampsia, gestational hypertension, or antepartum hemorrhage. METHODS: We searched the PubMed, Scopus, and ISI web of science from 1990 to Feb 2015. In addition, electronic literature searches supplemented by searching the gray literature (e.g., conference abstracts thesis and the result of technical reports) and scanning the reference lists of included studies and relevant systematic reviews. We explored statistical heterogeneity using the, I2 and tau-squared (Tau2) statistical tests. RESULTS: Eighteen studies were included. Preterm rupture of membranous (PROM), stillbirth, preeclampsia, eclampsia, gestational hypertension and antepartum hemorrhage were considerable outcomes in this survey. The results showed no significant association between inactive HB and these complications in pregnancy. The small amounts of P-value and chi-square and large amount of I2 suggested the probable heterogeneity in this part, which we tried to modify with statistical methods such as subgroup analysis. CONCLUSION: Inactive HB infection did not increase the risk of adversely mentioned outcomes in this study. Further, well-designed studies should be performed to confirm the results. |
format | Online Article Text |
id | pubmed-5439035 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Tehran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-54390352017-05-24 Inactive Hepatitis B Carrier and Pregnancy Outcomes: A Systematic Review and Meta–analysis KERAMAT, Afsaneh YOUNESIAN, Masud GHOLAMI FESHARAKI, Mohammad HASANI, Maryam MIRZAEI, Samaneh EBRAHIMI, Elham ALAVIAN, Seyed Moaed MOHAMMADI, Fatemeh Iran J Public Health Review Article BACKGROUND: We aimed to explore whether maternal asymptomatic hepatitis B (HB) infection effects on pre-term rupture of membranous (PROM), stillbirth, preeclampsia, eclampsia, gestational hypertension, or antepartum hemorrhage. METHODS: We searched the PubMed, Scopus, and ISI web of science from 1990 to Feb 2015. In addition, electronic literature searches supplemented by searching the gray literature (e.g., conference abstracts thesis and the result of technical reports) and scanning the reference lists of included studies and relevant systematic reviews. We explored statistical heterogeneity using the, I2 and tau-squared (Tau2) statistical tests. RESULTS: Eighteen studies were included. Preterm rupture of membranous (PROM), stillbirth, preeclampsia, eclampsia, gestational hypertension and antepartum hemorrhage were considerable outcomes in this survey. The results showed no significant association between inactive HB and these complications in pregnancy. The small amounts of P-value and chi-square and large amount of I2 suggested the probable heterogeneity in this part, which we tried to modify with statistical methods such as subgroup analysis. CONCLUSION: Inactive HB infection did not increase the risk of adversely mentioned outcomes in this study. Further, well-designed studies should be performed to confirm the results. Tehran University of Medical Sciences 2017-04 /pmc/articles/PMC5439035/ /pubmed/28540262 Text en Copyright© Iranian Public Health Association & Tehran University of Medical Sciences http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article KERAMAT, Afsaneh YOUNESIAN, Masud GHOLAMI FESHARAKI, Mohammad HASANI, Maryam MIRZAEI, Samaneh EBRAHIMI, Elham ALAVIAN, Seyed Moaed MOHAMMADI, Fatemeh Inactive Hepatitis B Carrier and Pregnancy Outcomes: A Systematic Review and Meta–analysis |
title | Inactive Hepatitis B Carrier and Pregnancy Outcomes: A Systematic Review and Meta–analysis |
title_full | Inactive Hepatitis B Carrier and Pregnancy Outcomes: A Systematic Review and Meta–analysis |
title_fullStr | Inactive Hepatitis B Carrier and Pregnancy Outcomes: A Systematic Review and Meta–analysis |
title_full_unstemmed | Inactive Hepatitis B Carrier and Pregnancy Outcomes: A Systematic Review and Meta–analysis |
title_short | Inactive Hepatitis B Carrier and Pregnancy Outcomes: A Systematic Review and Meta–analysis |
title_sort | inactive hepatitis b carrier and pregnancy outcomes: a systematic review and meta–analysis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439035/ https://www.ncbi.nlm.nih.gov/pubmed/28540262 |
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