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Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating HSP70 in SHSY-5Y cells

BACKGROUND: Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a new candidate growth factor for dopaminergic neurons against endoplasmic reticulum stress (ER stress). HSP70 family, a chaperon like heat shock protein family, was proved to be involved in the MANF induced survival pathway i...

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Detalles Bibliográficos
Autores principales: Sun, Hui, Jiang, Ming, Fu, Xing, Cai, Qiong, Zhang, Jingxing, Yin, Yanxin, Guo, Jia, Yu, Lihua, Jiang, Yun, Liu, Yigang, Feng, Liang, Nie, Zhiyu, Fang, Jianmin, Jin, Lingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439129/
https://www.ncbi.nlm.nih.gov/pubmed/28536652
http://dx.doi.org/10.1186/s40035-017-0082-8

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