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FDG PET-CT: Need for Vigilance in Patients Treated with Bleomycin

Bleomycin-induced interstitial lung disease is not a rare complication of treatment and may prove to be fatal if not suspected early in its course. As FDG PET-CT has become an essential clinical tool for interim and end-of-treatment response assessment in oncology, it is important that radiologists/...

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Autores principales: Paschali, Anna N, Gnanasegaran, Gopinath, Cook, Gary J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439189/
https://www.ncbi.nlm.nih.gov/pubmed/28533640
http://dx.doi.org/10.4103/0972-3919.202242
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author Paschali, Anna N
Gnanasegaran, Gopinath
Cook, Gary J
author_facet Paschali, Anna N
Gnanasegaran, Gopinath
Cook, Gary J
author_sort Paschali, Anna N
collection PubMed
description Bleomycin-induced interstitial lung disease is not a rare complication of treatment and may prove to be fatal if not suspected early in its course. As FDG PET-CT has become an essential clinical tool for interim and end-of-treatment response assessment in oncology, it is important that radiologists/nuclear medicine specialists be aware of the features of this potentially treatable condition so that treatment can be instigated during an early reversible phase before pulmonary damage has occurred. Herein, we report two cases of bleomycin toxicity featuring different patterns on the treatment-response assessment FDG PET-CT scan.
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spelling pubmed-54391892017-05-22 FDG PET-CT: Need for Vigilance in Patients Treated with Bleomycin Paschali, Anna N Gnanasegaran, Gopinath Cook, Gary J Indian J Nucl Med Case Report Bleomycin-induced interstitial lung disease is not a rare complication of treatment and may prove to be fatal if not suspected early in its course. As FDG PET-CT has become an essential clinical tool for interim and end-of-treatment response assessment in oncology, it is important that radiologists/nuclear medicine specialists be aware of the features of this potentially treatable condition so that treatment can be instigated during an early reversible phase before pulmonary damage has occurred. Herein, we report two cases of bleomycin toxicity featuring different patterns on the treatment-response assessment FDG PET-CT scan. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5439189/ /pubmed/28533640 http://dx.doi.org/10.4103/0972-3919.202242 Text en Copyright: © 2017 Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Paschali, Anna N
Gnanasegaran, Gopinath
Cook, Gary J
FDG PET-CT: Need for Vigilance in Patients Treated with Bleomycin
title FDG PET-CT: Need for Vigilance in Patients Treated with Bleomycin
title_full FDG PET-CT: Need for Vigilance in Patients Treated with Bleomycin
title_fullStr FDG PET-CT: Need for Vigilance in Patients Treated with Bleomycin
title_full_unstemmed FDG PET-CT: Need for Vigilance in Patients Treated with Bleomycin
title_short FDG PET-CT: Need for Vigilance in Patients Treated with Bleomycin
title_sort fdg pet-ct: need for vigilance in patients treated with bleomycin
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439189/
https://www.ncbi.nlm.nih.gov/pubmed/28533640
http://dx.doi.org/10.4103/0972-3919.202242
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