(18-)F-FDG PET/CT in Localizing Additional CNS Lesion in a Case of Langerhans Cell Histiocytosis: Determining Accurate Extent of the Disease

Central nervous system involvement is a rare manifestation of Langerhans cell histiocytosis (LCH), with bone and skin lesions being more frequent. MR remains the investigation of choice for localizing brain lesions. However, due to poor sensitivity of MRI in detecting osseous and pulmonary lesions,...

Descripción completa

Detalles Bibliográficos
Autores principales: Shamim, Shamim Ahmed, Tripathy, Sarthak, Mukherjee, Anirban, Bal, Chandrasekhar, Tripathi, Madhavi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439200/
https://www.ncbi.nlm.nih.gov/pubmed/28533655
http://dx.doi.org/10.4103/0972-3919.202253
_version_ 1783237902718730240
author Shamim, Shamim Ahmed
Tripathy, Sarthak
Mukherjee, Anirban
Bal, Chandrasekhar
Tripathi, Madhavi
author_facet Shamim, Shamim Ahmed
Tripathy, Sarthak
Mukherjee, Anirban
Bal, Chandrasekhar
Tripathi, Madhavi
author_sort Shamim, Shamim Ahmed
collection PubMed
description Central nervous system involvement is a rare manifestation of Langerhans cell histiocytosis (LCH), with bone and skin lesions being more frequent. MR remains the investigation of choice for localizing brain lesions. However, due to poor sensitivity of MRI in detecting osseous and pulmonary lesions, it is not used routinely in staging purposes until and unless indicated. We hereby discuss a case of 6-year-old boy of LCH who was referred for 18-F-FDG PET/CT for staging and knowing the extent of the disease, but a lesion in hypothalamus was picked up incidentally on FDG PET-CT study that was confirmed by MRI.
format Online
Article
Text
id pubmed-5439200
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-54392002017-05-22 (18-)F-FDG PET/CT in Localizing Additional CNS Lesion in a Case of Langerhans Cell Histiocytosis: Determining Accurate Extent of the Disease Shamim, Shamim Ahmed Tripathy, Sarthak Mukherjee, Anirban Bal, Chandrasekhar Tripathi, Madhavi Indian J Nucl Med Interesting Image Central nervous system involvement is a rare manifestation of Langerhans cell histiocytosis (LCH), with bone and skin lesions being more frequent. MR remains the investigation of choice for localizing brain lesions. However, due to poor sensitivity of MRI in detecting osseous and pulmonary lesions, it is not used routinely in staging purposes until and unless indicated. We hereby discuss a case of 6-year-old boy of LCH who was referred for 18-F-FDG PET/CT for staging and knowing the extent of the disease, but a lesion in hypothalamus was picked up incidentally on FDG PET-CT study that was confirmed by MRI. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5439200/ /pubmed/28533655 http://dx.doi.org/10.4103/0972-3919.202253 Text en Copyright: © 2017 Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Interesting Image
Shamim, Shamim Ahmed
Tripathy, Sarthak
Mukherjee, Anirban
Bal, Chandrasekhar
Tripathi, Madhavi
(18-)F-FDG PET/CT in Localizing Additional CNS Lesion in a Case of Langerhans Cell Histiocytosis: Determining Accurate Extent of the Disease
title (18-)F-FDG PET/CT in Localizing Additional CNS Lesion in a Case of Langerhans Cell Histiocytosis: Determining Accurate Extent of the Disease
title_full (18-)F-FDG PET/CT in Localizing Additional CNS Lesion in a Case of Langerhans Cell Histiocytosis: Determining Accurate Extent of the Disease
title_fullStr (18-)F-FDG PET/CT in Localizing Additional CNS Lesion in a Case of Langerhans Cell Histiocytosis: Determining Accurate Extent of the Disease
title_full_unstemmed (18-)F-FDG PET/CT in Localizing Additional CNS Lesion in a Case of Langerhans Cell Histiocytosis: Determining Accurate Extent of the Disease
title_short (18-)F-FDG PET/CT in Localizing Additional CNS Lesion in a Case of Langerhans Cell Histiocytosis: Determining Accurate Extent of the Disease
title_sort (18-)f-fdg pet/ct in localizing additional cns lesion in a case of langerhans cell histiocytosis: determining accurate extent of the disease
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439200/
https://www.ncbi.nlm.nih.gov/pubmed/28533655
http://dx.doi.org/10.4103/0972-3919.202253
work_keys_str_mv AT shamimshamimahmed 18ffdgpetctinlocalizingadditionalcnslesioninacaseoflangerhanscellhistiocytosisdeterminingaccurateextentofthedisease
AT tripathysarthak 18ffdgpetctinlocalizingadditionalcnslesioninacaseoflangerhanscellhistiocytosisdeterminingaccurateextentofthedisease
AT mukherjeeanirban 18ffdgpetctinlocalizingadditionalcnslesioninacaseoflangerhanscellhistiocytosisdeterminingaccurateextentofthedisease
AT balchandrasekhar 18ffdgpetctinlocalizingadditionalcnslesioninacaseoflangerhanscellhistiocytosisdeterminingaccurateextentofthedisease
AT tripathimadhavi 18ffdgpetctinlocalizingadditionalcnslesioninacaseoflangerhanscellhistiocytosisdeterminingaccurateextentofthedisease

Ejemplares similares