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Diffuse White Matter Signal Abnormalities on Magnetic Resonance Imaging Are Associated With Human Immunodeficiency Virus Type 1 Viral Escape in the Central Nervous System Among Patients With Neurological Symptoms

BACKGROUND. Human immunodeficiency virus type 1 (HIV-1) can replicate independently in extravascular compartments such as the central nervous system, resulting in either cerebrospinal fluid (CSF) discordance (viral load [VL] in CSF 0.5 log(10) copies HIV-1 RNA greater than plasma VL) or escape (dete...

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Detalles Bibliográficos
Autores principales:	Kugathasan, Ruthiran, Collier, Dami A., Haddow, Lewis J., El Bouzidi, Kate, Edwards, Simon G., Cartledge, Jonathan D., Miller, Robert F., Gupta, Ravindra K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Major Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439343/ https://www.ncbi.nlm.nih.gov/pubmed/28329096 http://dx.doi.org/10.1093/cid/cix035

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