Pertussis Antibody Transfer to Preterm Neonates After Second- Versus Third-Trimester Maternal Immunization

Preterm infants are most vulnerable to pertussis. Whether they might benefit from maternal immunization is unknown. Extending our previous results in term neonates, this observational study demonstrates that second- rather than third-trimester maternal vaccination results in higher birth anti–pertus...

Descripción completa

Detalles Bibliográficos
Autores principales: Eberhardt, Christiane S., Blanchard-Rohner, Geraldine, Lemaître, Barbara, Combescure, Christophe, Othenin-Girard, Véronique, Chilin, Antonina, Petre, Jean, Martinez de Tejada, Begoña, Siegrist, Claire-Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439344/
https://www.ncbi.nlm.nih.gov/pubmed/28329335
http://dx.doi.org/10.1093/cid/cix046
Descripción
Sumario:Preterm infants are most vulnerable to pertussis. Whether they might benefit from maternal immunization is unknown. Extending our previous results in term neonates, this observational study demonstrates that second- rather than third-trimester maternal vaccination results in higher birth anti–pertussis toxin titers in preterm neonates.

Ejemplares similares