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Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8
Regulation of intestinal T-cell responses is crucial for immune homeostasis and prevention of inflammatory bowel disease (IBD). A vital cytokine in regulating intestinal Tcells is transforming growth factor-β (TGFβ), which is secreted by cells as a latent complex that requires activation to function...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439516/ https://www.ncbi.nlm.nih.gov/pubmed/27782111 http://dx.doi.org/10.1038/mi.2016.94 |