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Identifying artemisinin resistance from parasite clearance half-life data with a simple Shiny web application

The emergence of artemisinin-resistant Plasmodium falciparum malaria is a major threat to malaria elimination. New tools for supporting the surveillance of artemisinin resistance are critical for current and future malaria control and elimination strategies. We have developed an open-access, user-fr...

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Detalles Bibliográficos
Autores principales: Tun, Sai Thein Than, Lubell, Yoel, Dondorp, Arjen M., Fieldman, Tom, Tun, Kyaw Myo, Celhay, Olivier, Chan, Xin Hui, Saralamba, Sompob, White, Lisa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439677/
https://www.ncbi.nlm.nih.gov/pubmed/28531230
http://dx.doi.org/10.1371/journal.pone.0177840
Descripción
Sumario:The emergence of artemisinin-resistant Plasmodium falciparum malaria is a major threat to malaria elimination. New tools for supporting the surveillance of artemisinin resistance are critical for current and future malaria control and elimination strategies. We have developed an open-access, user-friendly, web-based tool to analyse parasite clearance half-life data of P. falciparum infected patients after treatment with artemisinin derivatives, so that resistance to artemisinin can be identified. The tool can be accessed at bit.ly/id_artemisinin_resistance.