The metal nanoparticle-induced inflammatory response is regulated by SIRT1 through NF-κB deacetylation in aseptic loosening

Aseptic loosening is the most common cause of total hip arthroplasty (THA) failure, and osteolysis induced by wear particles plays a major role in aseptic loosening. Various pathways in multiple cell types contribute to the pathogenesis of osteolysis, but the role of Sirtuin 1 (SIRT1), which can reg...

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Detalles Bibliográficos
Autores principales: Deng, Zhantao, Jin, Jiewen, Wang, Zhenheng, Wang, Yong, Gao, Qian, Zhao, Jianning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439723/
https://www.ncbi.nlm.nih.gov/pubmed/28553103
http://dx.doi.org/10.2147/IJN.S124661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439723/
https://www.ncbi.nlm.nih.gov/pubmed/28553103
http://dx.doi.org/10.2147/IJN.S124661

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