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Is Zika Virus an Emerging TORCH Agent? An Invited Commentary
Zika virus (ZIKV) is a mosquito-borne arbovirus from the family Flaviviridae, which had caused some epidemics since its discovery in 1947 without any significant impacts on public health. In 2015, however, a 20-fold increase in congenital microcephaly cases in northeastern Brazil was attributed to p...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439991/ https://www.ncbi.nlm.nih.gov/pubmed/28579764 http://dx.doi.org/10.1177/1178122X17708993 |
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author | Mehrjardi, Mohammad Zare |
author_facet | Mehrjardi, Mohammad Zare |
author_sort | Mehrjardi, Mohammad Zare |
collection | PubMed |
description | Zika virus (ZIKV) is a mosquito-borne arbovirus from the family Flaviviridae, which had caused some epidemics since its discovery in 1947 without any significant impacts on public health. In 2015, however, a 20-fold increase in congenital microcephaly cases in northeastern Brazil was attributed to prenatally acquired ZIKV infection. Traditionally, TORCH agents have 4 common characteristics including causing a mild illness in infected mother, vertical transmission to fetus, developing several anomalies in the affected fetus, and in some instances, maternal therapy may not ameliorate fetal prognosis. Prenatal ZIKV infection has shown the aforementioned characteristics during the recent epidemics in South America and the Caribbean region; therefore, it should be considered as an emerging TORCH agent that may seriously threaten public health. Fetal ultrasound can be used as a safe, inexpensive, and easy-to-access imaging modality for detecting suspicious cases of congenital Zika syndrome in utero and suggesting confirmatory diagnostic examinations to these patients. |
format | Online Article Text |
id | pubmed-5439991 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-54399912017-06-02 Is Zika Virus an Emerging TORCH Agent? An Invited Commentary Mehrjardi, Mohammad Zare Virology (Auckl) Short Commentary Zika virus (ZIKV) is a mosquito-borne arbovirus from the family Flaviviridae, which had caused some epidemics since its discovery in 1947 without any significant impacts on public health. In 2015, however, a 20-fold increase in congenital microcephaly cases in northeastern Brazil was attributed to prenatally acquired ZIKV infection. Traditionally, TORCH agents have 4 common characteristics including causing a mild illness in infected mother, vertical transmission to fetus, developing several anomalies in the affected fetus, and in some instances, maternal therapy may not ameliorate fetal prognosis. Prenatal ZIKV infection has shown the aforementioned characteristics during the recent epidemics in South America and the Caribbean region; therefore, it should be considered as an emerging TORCH agent that may seriously threaten public health. Fetal ultrasound can be used as a safe, inexpensive, and easy-to-access imaging modality for detecting suspicious cases of congenital Zika syndrome in utero and suggesting confirmatory diagnostic examinations to these patients. SAGE Publications 2017-05-18 /pmc/articles/PMC5439991/ /pubmed/28579764 http://dx.doi.org/10.1177/1178122X17708993 Text en © The Author(s) 2017 This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Short Commentary Mehrjardi, Mohammad Zare Is Zika Virus an Emerging TORCH Agent? An Invited Commentary |
title | Is Zika Virus an Emerging TORCH Agent? An Invited Commentary |
title_full | Is Zika Virus an Emerging TORCH Agent? An Invited Commentary |
title_fullStr | Is Zika Virus an Emerging TORCH Agent? An Invited Commentary |
title_full_unstemmed | Is Zika Virus an Emerging TORCH Agent? An Invited Commentary |
title_short | Is Zika Virus an Emerging TORCH Agent? An Invited Commentary |
title_sort | is zika virus an emerging torch agent? an invited commentary |
topic | Short Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439991/ https://www.ncbi.nlm.nih.gov/pubmed/28579764 http://dx.doi.org/10.1177/1178122X17708993 |
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