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Insulin Receptor Signaling in POMC, but Not AgRP, Neurons Controls Adipose Tissue Insulin Action
Insulin is a key regulator of adipose tissue lipolysis, and impaired adipose tissue insulin action results in unrestrained lipolysis and lipotoxicity, which are hallmarks of the metabolic syndrome and diabetes. Insulin regulates adipose tissue metabolism through direct effects on adipocytes and thro...
Autores principales: | Shin, Andrew C., Filatova, Nika, Lindtner, Claudia, Chi, Tiffany, Degann, Seta, Oberlin, Douglas, Buettner, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440019/ https://www.ncbi.nlm.nih.gov/pubmed/28385803 http://dx.doi.org/10.2337/db16-1238 |
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