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Comparative Pathogenesis of Autoimmune Diabetes in Humans, NOD Mice, and Canines: Has a Valuable Animal Model of Type 1 Diabetes Been Overlooked?
Despite decades of research in humans and mouse models of disease, substantial gaps remain in our understanding of pathogenic mechanisms underlying the development of type 1 diabetes. Furthermore, translation of therapies from preclinical efforts capable of delaying or halting β-cell destruction has...
Autores principales: | O’Kell, Allison L., Wasserfall, Clive, Catchpole, Brian, Davison, Lucy J., Hess, Rebecka S., Kushner, Jake A., Atkinson, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440022/ https://www.ncbi.nlm.nih.gov/pubmed/28533295 http://dx.doi.org/10.2337/db16-1551 |
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