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Comparative Pathogenesis of Autoimmune Diabetes in Humans, NOD Mice, and Canines: Has a Valuable Animal Model of Type 1 Diabetes Been Overlooked?

Despite decades of research in humans and mouse models of disease, substantial gaps remain in our understanding of pathogenic mechanisms underlying the development of type 1 diabetes. Furthermore, translation of therapies from preclinical efforts capable of delaying or halting β-cell destruction has...

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Detalles Bibliográficos
Autores principales: O’Kell, Allison L., Wasserfall, Clive, Catchpole, Brian, Davison, Lucy J., Hess, Rebecka S., Kushner, Jake A., Atkinson, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440022/
https://www.ncbi.nlm.nih.gov/pubmed/28533295
http://dx.doi.org/10.2337/db16-1551

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