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Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host
Similar to other yeasts, the human pathogen Candida glabrata ages when it undergoes asymmetric, finite cell divisions, which determines its replicative lifespan. We sought to investigate if and how aging changes resilience of C. glabrata populations in the host environment. Our data demonstrate that...
Autores principales: | Bouklas, Tejas, Alonso-Crisóstomo, Luz, Székely, Tamás, Diago-Navarro, Elizabeth, Orner, Erika P., Smith, Kalie, Munshi, Mansa A., Del Poeta, Maurizio, Balázsi, Gábor, Fries, Bettina C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440053/ https://www.ncbi.nlm.nih.gov/pubmed/28489916 http://dx.doi.org/10.1371/journal.ppat.1006355 |
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