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Infected tibia defect fractures treated with the Masquelet technique

The treatment after open and infected fractures with extensive soft tissue damage and bone deficit remains a challenging clinical problem. The technique described by Masquelet, using a temporary cement spacer to induce a membrane combined with reconstructive soft tissue coverage, is a possible solut...

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Autores principales: Mühlhäusser, Julia, Winkler, Jörg, Babst, Reto, Beeres, Frank J.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440151/
https://www.ncbi.nlm.nih.gov/pubmed/28514314
http://dx.doi.org/10.1097/MD.0000000000006948
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author Mühlhäusser, Julia
Winkler, Jörg
Babst, Reto
Beeres, Frank J.P.
author_facet Mühlhäusser, Julia
Winkler, Jörg
Babst, Reto
Beeres, Frank J.P.
author_sort Mühlhäusser, Julia
collection PubMed
description The treatment after open and infected fractures with extensive soft tissue damage and bone deficit remains a challenging clinical problem. The technique described by Masquelet, using a temporary cement spacer to induce a membrane combined with reconstructive soft tissue coverage, is a possible solution. This study describes the work-up, operative procedure, complications, and the outcome of a homogenous group of patients with an open and infected tibia fracture and segmental bone loss treated with the Masquelet technique (MT). This retrospective study evaluates patients having sustained an open tibia fracture treated with the MT between 2008 and 2013 with a follow up of at least 1 year. The defect was either primary, caused by a high-grade open fracture or secondary due to a non-union after an open fracture. Prerequisite conditions prior to the procedure of the Masquelet were a defect zone with eradicated infection, an intact soft tissue cover and stability provided by an external fixation. Volume of the defect, time until the implantation of the spacer, time of the spacer in situ and the time to clinical and radiological union were evaluated. Patient records were screened for reoperations and complications. The functional clinical outcome was measured. Eight patients were treated with a follow up over 1 year. The spacer was implanted after a median of 11 (2–70) weeks after the accident. The predefined conditions for the Masquelet phase were reached after a median of 12 (7–34) operations. Seven patients required reconstructive soft tissue coverage. The volume of the defect had a median of 111 (53.9–621.6) cm(3), the spacer was in situ for a median of 12 (7–26) weeks. Radiological healing was achieved in 7 cases after a median time of 52 (26–93) weeks. Full weight bearing was achieved after a median time of 16 (11–24) weeks. Four patients needed a reoperation. The lower limb functional index was a median of 60% (32–92%). Seven out of 8 patients treated in this group of severe open and infected tibia fractures did both clinically and radiologically heal. Due to the massive destruction of the soft tissue, patients needed several reoperations with soft tissue debridements and reconstruction before the spacer and the bone graft could be implanted.
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spelling pubmed-54401512017-05-25 Infected tibia defect fractures treated with the Masquelet technique Mühlhäusser, Julia Winkler, Jörg Babst, Reto Beeres, Frank J.P. Medicine (Baltimore) 7100 The treatment after open and infected fractures with extensive soft tissue damage and bone deficit remains a challenging clinical problem. The technique described by Masquelet, using a temporary cement spacer to induce a membrane combined with reconstructive soft tissue coverage, is a possible solution. This study describes the work-up, operative procedure, complications, and the outcome of a homogenous group of patients with an open and infected tibia fracture and segmental bone loss treated with the Masquelet technique (MT). This retrospective study evaluates patients having sustained an open tibia fracture treated with the MT between 2008 and 2013 with a follow up of at least 1 year. The defect was either primary, caused by a high-grade open fracture or secondary due to a non-union after an open fracture. Prerequisite conditions prior to the procedure of the Masquelet were a defect zone with eradicated infection, an intact soft tissue cover and stability provided by an external fixation. Volume of the defect, time until the implantation of the spacer, time of the spacer in situ and the time to clinical and radiological union were evaluated. Patient records were screened for reoperations and complications. The functional clinical outcome was measured. Eight patients were treated with a follow up over 1 year. The spacer was implanted after a median of 11 (2–70) weeks after the accident. The predefined conditions for the Masquelet phase were reached after a median of 12 (7–34) operations. Seven patients required reconstructive soft tissue coverage. The volume of the defect had a median of 111 (53.9–621.6) cm(3), the spacer was in situ for a median of 12 (7–26) weeks. Radiological healing was achieved in 7 cases after a median time of 52 (26–93) weeks. Full weight bearing was achieved after a median time of 16 (11–24) weeks. Four patients needed a reoperation. The lower limb functional index was a median of 60% (32–92%). Seven out of 8 patients treated in this group of severe open and infected tibia fractures did both clinically and radiologically heal. Due to the massive destruction of the soft tissue, patients needed several reoperations with soft tissue debridements and reconstruction before the spacer and the bone graft could be implanted. Wolters Kluwer Health 2017-05-19 /pmc/articles/PMC5440151/ /pubmed/28514314 http://dx.doi.org/10.1097/MD.0000000000006948 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0, which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0
spellingShingle 7100
Mühlhäusser, Julia
Winkler, Jörg
Babst, Reto
Beeres, Frank J.P.
Infected tibia defect fractures treated with the Masquelet technique
title Infected tibia defect fractures treated with the Masquelet technique
title_full Infected tibia defect fractures treated with the Masquelet technique
title_fullStr Infected tibia defect fractures treated with the Masquelet technique
title_full_unstemmed Infected tibia defect fractures treated with the Masquelet technique
title_short Infected tibia defect fractures treated with the Masquelet technique
title_sort infected tibia defect fractures treated with the masquelet technique
topic 7100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440151/
https://www.ncbi.nlm.nih.gov/pubmed/28514314
http://dx.doi.org/10.1097/MD.0000000000006948
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