Cargando…

The efficacy of steroids for postoperative persistent inflammatory reaction in a patient with barium peritonitis: A case report

INTRODUCTION: Barium peritonitis is a serious and life-threatening disease requiring intensive care. Residual barium in the intraperitoneal cavity can cause persistent inflammation, postoperatively. PRESENTATION OF CASE: An 80-year-old woman was admitted to our hospital because of abdominal pain and...

Descripción completa

Detalles Bibliográficos
Autores principales: Kojima, Hirofumi, Hojo, Shozo, Manabe, Takahiro, Demura, Shiori, Sekine, Shinichi, Shibuya, Kazuto, Hashimoto, Isaya, Yoshioka, Isaku, Okumura, Tomoyuki, Nagata, Takuya, Fujii, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440279/
https://www.ncbi.nlm.nih.gov/pubmed/28531867
http://dx.doi.org/10.1016/j.ijscr.2017.05.012
_version_ 1783238034976669696
author Kojima, Hirofumi
Hojo, Shozo
Manabe, Takahiro
Demura, Shiori
Sekine, Shinichi
Shibuya, Kazuto
Hashimoto, Isaya
Yoshioka, Isaku
Okumura, Tomoyuki
Nagata, Takuya
Fujii, Tsutomu
author_facet Kojima, Hirofumi
Hojo, Shozo
Manabe, Takahiro
Demura, Shiori
Sekine, Shinichi
Shibuya, Kazuto
Hashimoto, Isaya
Yoshioka, Isaku
Okumura, Tomoyuki
Nagata, Takuya
Fujii, Tsutomu
author_sort Kojima, Hirofumi
collection PubMed
description INTRODUCTION: Barium peritonitis is a serious and life-threatening disease requiring intensive care. Residual barium in the intraperitoneal cavity can cause persistent inflammation, postoperatively. PRESENTATION OF CASE: An 80-year-old woman was admitted to our hospital because of abdominal pain and vomiting after barium meal examination. Physical and radiographic examination showed sigmoid colon perforation. Barium sulfate extravasation was noted in the intraperitoneal cavity. We diagnosed the patient with barium peritonitis, and performed Hartmann’s procedure and thorough lavage of the intraperitoneal cavity with 20-L saline. Postoperative blood examination results were not readily improved because of the residual barium in the intraperitoneal and retroperitoneal cavities. We excluded the presence of any other inflammation origin, except that from residual barium. Methylprednisolone 500 mg/body/day was administered for 3 days and the dose was gradually decreased thereafter. The white blood cell count and serum C-reactive protein levels immediately improved to normal levels. DISCUSSION: Barium peritonitis is associated with high mortality. Residual barium in the intraperitoneal cavity can cause chemical peritonitis, leading to granuloma formation and ileus, postoperatively. Therefore, complete removal of barium in the abdominal cavity with aggressive drainage and large quantity of saline is necessary to prevent postoperative inflammatory reaction. The use of steroids improves the persistent inflammation caused by residual barium, unless any infectious origins are present, which can worsen with steroid-use. CONCLUSION: Residual barium in the intraperitoneal cavity causes persistent inflammatory reaction in patients with barium peritonitis. The use of steroids is effective for postoperative persistent inflammation due to the residual barium.
format Online
Article
Text
id pubmed-5440279
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-54402792017-05-30 The efficacy of steroids for postoperative persistent inflammatory reaction in a patient with barium peritonitis: A case report Kojima, Hirofumi Hojo, Shozo Manabe, Takahiro Demura, Shiori Sekine, Shinichi Shibuya, Kazuto Hashimoto, Isaya Yoshioka, Isaku Okumura, Tomoyuki Nagata, Takuya Fujii, Tsutomu Int J Surg Case Rep Case Report INTRODUCTION: Barium peritonitis is a serious and life-threatening disease requiring intensive care. Residual barium in the intraperitoneal cavity can cause persistent inflammation, postoperatively. PRESENTATION OF CASE: An 80-year-old woman was admitted to our hospital because of abdominal pain and vomiting after barium meal examination. Physical and radiographic examination showed sigmoid colon perforation. Barium sulfate extravasation was noted in the intraperitoneal cavity. We diagnosed the patient with barium peritonitis, and performed Hartmann’s procedure and thorough lavage of the intraperitoneal cavity with 20-L saline. Postoperative blood examination results were not readily improved because of the residual barium in the intraperitoneal and retroperitoneal cavities. We excluded the presence of any other inflammation origin, except that from residual barium. Methylprednisolone 500 mg/body/day was administered for 3 days and the dose was gradually decreased thereafter. The white blood cell count and serum C-reactive protein levels immediately improved to normal levels. DISCUSSION: Barium peritonitis is associated with high mortality. Residual barium in the intraperitoneal cavity can cause chemical peritonitis, leading to granuloma formation and ileus, postoperatively. Therefore, complete removal of barium in the abdominal cavity with aggressive drainage and large quantity of saline is necessary to prevent postoperative inflammatory reaction. The use of steroids improves the persistent inflammation caused by residual barium, unless any infectious origins are present, which can worsen with steroid-use. CONCLUSION: Residual barium in the intraperitoneal cavity causes persistent inflammatory reaction in patients with barium peritonitis. The use of steroids is effective for postoperative persistent inflammation due to the residual barium. Elsevier 2017-05-15 /pmc/articles/PMC5440279/ /pubmed/28531867 http://dx.doi.org/10.1016/j.ijscr.2017.05.012 Text en © 2017 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kojima, Hirofumi
Hojo, Shozo
Manabe, Takahiro
Demura, Shiori
Sekine, Shinichi
Shibuya, Kazuto
Hashimoto, Isaya
Yoshioka, Isaku
Okumura, Tomoyuki
Nagata, Takuya
Fujii, Tsutomu
The efficacy of steroids for postoperative persistent inflammatory reaction in a patient with barium peritonitis: A case report
title The efficacy of steroids for postoperative persistent inflammatory reaction in a patient with barium peritonitis: A case report
title_full The efficacy of steroids for postoperative persistent inflammatory reaction in a patient with barium peritonitis: A case report
title_fullStr The efficacy of steroids for postoperative persistent inflammatory reaction in a patient with barium peritonitis: A case report
title_full_unstemmed The efficacy of steroids for postoperative persistent inflammatory reaction in a patient with barium peritonitis: A case report
title_short The efficacy of steroids for postoperative persistent inflammatory reaction in a patient with barium peritonitis: A case report
title_sort efficacy of steroids for postoperative persistent inflammatory reaction in a patient with barium peritonitis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440279/
https://www.ncbi.nlm.nih.gov/pubmed/28531867
http://dx.doi.org/10.1016/j.ijscr.2017.05.012
work_keys_str_mv AT kojimahirofumi theefficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT hojoshozo theefficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT manabetakahiro theefficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT demurashiori theefficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT sekineshinichi theefficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT shibuyakazuto theefficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT hashimotoisaya theefficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT yoshiokaisaku theefficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT okumuratomoyuki theefficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT nagatatakuya theefficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT fujiitsutomu theefficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT kojimahirofumi efficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT hojoshozo efficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT manabetakahiro efficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT demurashiori efficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT sekineshinichi efficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT shibuyakazuto efficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT hashimotoisaya efficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT yoshiokaisaku efficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT okumuratomoyuki efficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT nagatatakuya efficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport
AT fujiitsutomu efficacyofsteroidsforpostoperativepersistentinflammatoryreactioninapatientwithbariumperitonitisacasereport