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Hepatocyte-specific expression of constitutively active Alk5 exacerbates thioacetamide-induced liver injury in mice

While Transforming growth factor-βs (Tgf-βs) have been known to play an important role in liver fibrosis through an activation of Hepatic Stellate Cells (HSC), their fibrotic role on hepatocytes in liver damage has not been addressed thoroughly. To shed more light on the hepatocyte-specific role of...

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Detalles Bibliográficos
Autores principales: Kongphat, Wanthita, Pudgerd, Arnon, Sridurongrit, Somyoth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440359/
https://www.ncbi.nlm.nih.gov/pubmed/28560358
http://dx.doi.org/10.1016/j.heliyon.2017.e00305