Scopolin ameliorates high-fat diet induced hepatic steatosis in mice: potential involvement of SIRT1-mediated signaling cascades in the liver

The present study aimed to investigate whether scopolin exhibits beneficial effects on high-fat diet (HFD)-induced hepatic steatosis in mice. The involvement of sirtuin 1 (SIRT1) as a molecular target for scopolin was also explored. Scopolin decreased the Km of SIRT1 for p53 and nicotinamide adenine...

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Detalles Bibliográficos
Autores principales: Yoo, Ahyoung, Narayan, Vikram P., Hong, Eun Young, Whang, Wan Kyunn, Park, Taesun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440403/
https://www.ncbi.nlm.nih.gov/pubmed/28533555
http://dx.doi.org/10.1038/s41598-017-02416-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440403/
https://www.ncbi.nlm.nih.gov/pubmed/28533555
http://dx.doi.org/10.1038/s41598-017-02416-6

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