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Scopolin ameliorates high-fat diet induced hepatic steatosis in mice: potential involvement of SIRT1-mediated signaling cascades in the liver

The present study aimed to investigate whether scopolin exhibits beneficial effects on high-fat diet (HFD)-induced hepatic steatosis in mice. The involvement of sirtuin 1 (SIRT1) as a molecular target for scopolin was also explored. Scopolin decreased the Km of SIRT1 for p53 and nicotinamide adenine...

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Detalles Bibliográficos
Autores principales:	Yoo, Ahyoung, Narayan, Vikram P., Hong, Eun Young, Whang, Wan Kyunn, Park, Taesun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440403/ https://www.ncbi.nlm.nih.gov/pubmed/28533555 http://dx.doi.org/10.1038/s41598-017-02416-6

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