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CD47 surface stability is sensitive to actin disruption prior to inclusion within the band 3 macrocomplex

CD47 is an important ‘marker of self’ protein with multiple isoforms produced though alternative splicing that exhibit tissue-specific expression. Mature erythrocytes express CD47 isoform 2 only, with membrane stability of this version dependent on inclusion within the band 3 macrocomplex, via prote...

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Detalles Bibliográficos
Autores principales: Mordue, Kathryn E., Hawley, Bethan R., Satchwell, Timothy J., Toye, Ashley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440412/
https://www.ncbi.nlm.nih.gov/pubmed/28533511
http://dx.doi.org/10.1038/s41598-017-02356-1