Cargando…

YXQN Reduces Alzheimer’s Disease-Like Pathology and Cognitive Decline in APPswePS1dE9 Transgenic Mice

Alzheimer’s disease (AD) is the world’s most common form of dementia, in which aggregation of amyloid-β (Aβ) is the hallmark. Unfortunately, few medicines have succeeded to completely cure AD. Yangxue Qingnao (YXQN) is a Chinese traditional medicine, and its pharmacological effect is improving cereb...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xiaowan, Song, Runmin, Lu, Wenliang, Liu, Ziyu, Wang, Lichun, Zhu, Xiaojuan, Liu, Yanjun, Sun, Zijie, Li, Jiang, Li, Xiaomeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440527/ https://www.ncbi.nlm.nih.gov/pubmed/28603494 http://dx.doi.org/10.3389/fnagi.2017.00157

Ejemplares similares

Longitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic mice
por: François, Arnaud, et al.
Publicado: (2014)

Motor Cortex Theta and Gamma Architecture in Young Adult APPswePS1dE9 Alzheimer Mice
por: Papazoglou, Anna, et al.
Publicado: (2017)

Mechanisms Mediating the Protective Effects of Eicosapentaenoic Acid in Brain of the APPswePS1dE9 Alzheimer's Mouse Model
por: Yavari, Mahsa, et al.
Publicado: (2022)

Gender-Specific Hippocampal Dysrhythmia and Aberrant Hippocampal and Cortical Excitability in the APPswePS1dE9 Model of Alzheimer's Disease
por: Papazoglou, Anna, et al.
Publicado: (2016)

Reactive astrocytes as treatment targets in Alzheimer's disease—Systematic review of studies using the APPswePS1dE9 mouse model
por: Smit, Tamar, et al.
Publicado: (2021)

Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice
por: Mellott, Tiffany J., et al.
Publicado: (2017)

Correction: Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice
por: Mellott, Tiffany J., et al.
Publicado: (2017)

IGF2 Ameliorates Amyloidosis, Increases Cholinergic Marker Expression and Raises BMP9 and Neurotrophin Levels in the Hippocampus of the APPswePS1dE9 Alzheimer’s Disease Model Mice
por: Mellott, Tiffany J., et al.
Publicado: (2014)

Identification of Intron Retention in the Slc16a3 Gene Transcript Encoding the Transporter MCT4 in the Brain of Aged and Alzheimer-Disease Model (APPswePS1dE9) Mice
por: EL-Seedy, Ayman, et al.
Publicado: (2023)

Mitochondrial biogenesis mediated by melatonin in an APPswe/PS1dE9 transgenic mice model
por: Song, ChaoYuan, et al.
Publicado: (2018)

Crocetin attenuates inflammation and amyloid-β accumulation in APPsw transgenic mice
por: Zhang, Jin, et al.
Publicado: (2018)

Transcriptome analysis of fasudil treatment in the APPswe/PSEN1dE9 transgenic (APP/PS1) mice model of Alzheimer’s disease
por: Yan, Hailong, et al.
Publicado: (2022)

nAChRs gene expression and neuroinflammation in APPswe/PS1dE9 transgenic mouse
por: D’Angelo, Chiara, et al.
Publicado: (2021)

The influence of GAPT extraction on synapse loss of APPswe/PS1dE9 transgenic mice via adjusting Bcl-2/Bax balance
por: Shi, Jing, et al.
Publicado: (2018)

Dexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways
por: Ettcheto, Miren, et al.
Publicado: (2017)

Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer’s disease-related pathologies in APPswe/PS1dE9 transgenic mice
por: Tsai-Teng, Tzeng, et al.
Publicado: (2016)

Mitochondrial dynamics changes with age in an APPsw/PS1dE9 mouse model of Alzheimer’s disease
por: Xu, Lin-Lin, et al.
Publicado: (2017)

Publisher Correction: nAChRs gene expression and neuroinflammation in APPswe/PS1dE9 transgenic mouse
por: D’Angelo, Chiara, et al.
Publicado: (2021)

Utilization of APPswe/PS1dE9 Transgenic Mice in Research of Alzheimer's Disease: Focus on Gene Therapy and Cell-Based Therapy Applications
por: Malm, Tarja, et al.
Publicado: (2011)

Analysis of differential plaque depositions in the brains of Tg2576 and Tg-APPswe/PS1dE9 transgenic mouse models of Alzheimer disease
por: Kim, Tae-Kyung, et al.
Publicado: (2012)

High fat diet exacerbates Alzheimer's disease-related pathology in APPswe/PS1 mice
por: Thériault, Peter, et al.
Publicado: (2016)

The Protective Effect of Vanadium on Cognitive Impairment and the Neuropathology of Alzheimer’s Disease in APPSwe/PS1dE9 Mice
por: He, Zhijun, et al.
Publicado: (2020)

Long-Term Sex- and Genotype-Specific Effects of (56)Fe Irradiation on Wild-Type and APPswe/PS1dE9 Transgenic Mice
por: Schroeder, Maren K., et al.
Publicado: (2021)

Outstanding Phenotypic Differences in the Profile of Amyloid-β between Tg2576 and APPswe/PS1dE9 Transgenic Mouse Models of Alzheimer’s Disease
por: Allué, José Antonio, et al.
Publicado: (2016)

Retinal Levels of Amyloid Beta Correlate with Cerebral Levels of Amyloid Beta in Young APPswe/PS1dE9 Transgenic Mice before Onset of Alzheimer's Disease
por: Mei, Xi, et al.
Publicado: (2020)

Cardiomyocyte Contractile Dysfunction in the APPswe/PS1dE9 Mouse Model of Alzheimer's Disease
por: Turdi, Subat, et al.
Publicado: (2009)

Cyanidin-3-O-glucoside protects the brain and improves cognitive function in APPswe/PS1ΔE9 transgenic mice model
por: Baek, Hana, et al.
Publicado: (2023)

Augmented Insulin and Leptin Resistance of High Fat Diet-Fed APPswe/PS1dE9 Transgenic Mice Exacerbate Obesity and Glycemic Dysregulation
por: Lee, Yi-Heng, et al.
Publicado: (2018)

Amyloid pathology induces dysfunction of systemic neurotransmission in aged APPswe/PS2 mice
por: Oh, Se Jong, et al.
Publicado: (2022)

Dietary lactoferrin has differential effects on gut microbiota in young versus middle-aged APPswe/PS1dE9 transgenic mice but no effects on cognitive function
por: Zhou, Huan-Huan, et al.
Publicado: (2021)

Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic mice
por: Wang, Fei, et al.
Publicado: (2015)

Genome-Wide Analysis of miRNA Signature in the APPswe/PS1ΔE9 Mouse Model of Alzheimer's Disease
por: Luo, Hongxue, et al.
Publicado: (2014)

Curcumin improves memory deficits by inhibiting HMGB1‐RAGE/TLR4‐NF‐κB signalling pathway in APPswe/PS1dE9 transgenic mice hippocampus
por: Han, Yuan, et al.
Publicado: (2021)

Corrigendum: Amyloid pathology induces dysfunction of systemic neurotransmission in aged APPswe/PS2 mice
por: Oh, Se Jong, et al.
Publicado: (2022)

Cattle encephalon glycoside and ignotin injection improves cognitive impairment in APPswe/PS1dE9 mice used as multitarget anti-Alzheimer’s drug candidates
por: Gao, Ya, et al.
Publicado: (2015)

Microvascular ultrastructural changes precede cognitive impairment in the murine APPswe/PS1dE9 model of Alzheimer’s disease
por: Kelly, Patricia, et al.
Publicado: (2017)

Andrographolide promotes hippocampal neurogenesis and spatial memory in the APPswe/PS1ΔE9 mouse model of Alzheimer’s disease
por: Arredondo, Sebastian B., et al.
Publicado: (2021)

Vitamin D(2)-Enriched Button Mushroom (Agaricus bisporus) Improves Memory in Both Wild Type and APPswe/PS1dE9 Transgenic Mice
por: Bennett, Louise, et al.
Publicado: (2013)

Amelioration of cognitive impairments in APPswe/PS1dE9 mice is associated with metabolites alteration induced by total salvianolic acid
por: Shen, Li, et al.
Publicado: (2017)

Curcumin regulates insulin pathways and glucose metabolism in the brains of APPswe/PS1dE9 mice
por: Wang, Pengwen, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_cb871sots1no4mvkoogqtvqebf