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Hyperglycemia-induced Renal P2X7 Receptor Activation Enhances Diabetes-related Injury
Diabetes is a leading cause of renal disease. Glomerular mesangial expansion and fibrosis are hallmarks of diabetic nephropathy and this is thought to be promoted by infiltration of circulating macrophages. Monocyte chemoattractant protein-1 (MCP-1) has been shown to attract macrophages in kidney di...
Autores principales: | Menzies, Robert I., Booth, John W.R., Mullins, John J., Bailey, Matthew A., Tam, Frederick W.K., Norman, Jill T., Unwin, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440600/ https://www.ncbi.nlm.nih.gov/pubmed/28434946 http://dx.doi.org/10.1016/j.ebiom.2017.04.011 |
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