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Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within Tumors

Metabolic alteration constitutes a hallmark of cancer. Glycolysis and antioxidant pathways in kidney cancer are elevated, with frequent mutation of the VHL gene. Intratumor genetic heterogeneity has been recently demonstrated in kidney cancer. However, intratumor metabolic heterogeneity has not been...

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Detalles Bibliográficos
Autores principales:	Okegawa, Takatsugu, Morimoto, Megumi, Nishizawa, Satoru, Kitazawa, Satoshi, Honda, Kohei, Araki, Hideo, Tamura, Toshiya, Ando, Ayumi, Satomi, Yoshinori, Nutahara, Kikuo, Hara, Takahito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440602/ https://www.ncbi.nlm.nih.gov/pubmed/28408240 http://dx.doi.org/10.1016/j.ebiom.2017.04.009

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