In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity

The relatively recent discovery and characterization of human broadly neutralizing antibodies (bnAbs) against influenza virus provide valuable insights into antiviral and vaccine development. However, the factors that influence the evolution of high-affinity bnAbs remain elusive. We therefore explor...

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Detalles Bibliográficos
Autores principales: Wu, Nicholas C., Grande, Geramie, Turner, Hannah L., Ward, Andrew B., Xie, Jia, Lerner, Richard A., Wilson, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440694/
https://www.ncbi.nlm.nih.gov/pubmed/28504265
http://dx.doi.org/10.1038/ncomms15371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440694/
https://www.ncbi.nlm.nih.gov/pubmed/28504265
http://dx.doi.org/10.1038/ncomms15371

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