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Simulated rRNA/DNA Ratios Show Potential To Misclassify Active Populations as Dormant

The use of rRNA/DNA ratios derived from surveys of rRNA sequences in RNA and DNA extracts is an appealing but poorly validated approach to infer the activity status of environmental microbes. To improve the interpretation of rRNA/DNA ratios, we performed simulations to investigate the effects of com...

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Detalles Bibliográficos
Autores principales: Steven, Blaire, Hesse, Cedar, Soghigian, John, Gallegos-Graves, La Verne, Dunbar, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440720/
https://www.ncbi.nlm.nih.gov/pubmed/28363969
http://dx.doi.org/10.1128/AEM.00696-17

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