Mutant KRAS promotes malignant pleural effusion formation

Malignant pleural effusion (MPE) is the lethal consequence of various human cancers metastatic to the pleural cavity. However, the mechanisms responsible for the development of MPE are still obscure. Here we show that mutant KRAS is important for MPE induction in mice. Pleural disseminated, mutant K...

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Detalles Bibliográficos
Autores principales: Αgalioti, Theodora, Giannou, Anastasios D., Krontira, Anthi C., Kanellakis, Nikolaos I., Kati, Danai, Vreka, Malamati, Pepe, Mario, Spella, Μagda, Lilis, Ioannis, Zazara, Dimitra E., Nikolouli, Eirini, Spiropoulou, Nikolitsa, Papadakis, Andreas, Papadia, Konstantina, Voulgaridis, Apostolos, Harokopos, Vaggelis, Stamou, Panagiota, Meiners, Silke, Eickelberg, Oliver, Snyder, Linda A., Antimisiaris, Sophia G., Kardamakis, Dimitrios, Psallidas, Ioannis, Μarazioti, Antonia, Stathopoulos, Georgios T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440809/
https://www.ncbi.nlm.nih.gov/pubmed/28508873
http://dx.doi.org/10.1038/ncomms15205

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