Actin stress fiber organization promotes cell stiffening and proliferation of pre-invasive breast cancer cells

Studies of the role of actin in tumour progression have highlighted its key contribution in cell softening associated with cell invasion. Here, using a human breast cell line with conditional Src induction, we demonstrate that cells undergo a stiffening state prior to acquiring malignant features. T...

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Detalles Bibliográficos
Autores principales: Tavares, Sandra, Vieira, André Filipe, Taubenberger, Anna Verena, Araújo, Margarida, Martins, Nuno Pimpao, Brás-Pereira, Catarina, Polónia, António, Herbig, Maik, Barreto, Clara, Otto, Oliver, Cardoso, Joana, Pereira-Leal, José B., Guck, Jochen, Paredes, Joana, Janody, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440822/
https://www.ncbi.nlm.nih.gov/pubmed/28508872
http://dx.doi.org/10.1038/ncomms15237

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