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Influence of Folate-Related Gene Polymorphisms on High-Dose Methotrexate-Related Toxicity and Prognosis in Turkish Children with Acute Lymphoblastic Leukemia

OBJECTIVE: High-dose methotrexate (HD-MTX) is widely used in the consolidation phase of childhood acute lymphoblastic leukemia (ALL), but the roles that polymorphisms in folate-related genes (FRGs) play in HD-MTX toxicity and prognosis in children with ALL are not understood. The aims of this study...

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Detalles Bibliográficos
Autores principales:	Yazıcıoğlu, Burcu, Kaya, Zühre, Güntekin Ergun, Sezen, Perçin, Ferda, Koçak, Ülker, Yenicesu, İdil, Gürsel, Türkiz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Galenos Publishing 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440866/ https://www.ncbi.nlm.nih.gov/pubmed/27094381 http://dx.doi.org/10.4274/tjh.2016.0007

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