Association Between N363S and BclI Polymorphisms of the Glucocorticoid Receptor Gene (NR3C1) and Glucocorticoid Side Effects During Childhood Acute Lymphoblastic Leukemia Treatment

OBJECTIVE: Glucocorticoids (GCs) are the key drugs for the treatment of pediatric acute lymphoblastic leukemia (ALL). Herein, investigation of the relationship between the N363S and BclI polymorphisms of the GC receptor gene (NR3C1) and the side effects of GCs during pediatric ALL therapy was aimed....

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Detalles Bibliográficos
Autores principales: Kaymak Cihan, Meriç, Karabulut, Halil Gürhan, Yürür Kutlay, Nüket, Ilgın Ruhi, Hatice, Tükün, Ajlan, Olcay, Lale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440867/
https://www.ncbi.nlm.nih.gov/pubmed/28179212
http://dx.doi.org/10.4274/tjh.2016.0253

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