Impaired glucose tolerance attenuates bone accrual by promoting the maturation of osteoblasts: Role of Beclin1-mediated autophagy

Patients with type 2 diabetes mellitus (T2DM) experience a 1.5–3.5 fold increase in fracture risk, but the mechanisms responsible for these alterations in bone biomechanical properties remain elusive. Macroautophagy, often referred to as autophagy, is regulated by signaling downstream of the insulin...

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Detalles Bibliográficos
Autores principales: Rendina-Ruedy, E., Graef, J.L., Lightfoot, S.A., Ritchey, J.W., Clarke, S.L., Lucas, E.A., Smith, B.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440954/
https://www.ncbi.nlm.nih.gov/pubmed/28580387
http://dx.doi.org/10.1016/j.bonr.2016.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440954/
https://www.ncbi.nlm.nih.gov/pubmed/28580387
http://dx.doi.org/10.1016/j.bonr.2016.08.001

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