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Genetic risk score based on the prevalence of vertebral fracture in Japanese women with osteoporosis

A genetic risk score (GRS) was developed for predicting fracture risk based on the prevalence of vertebral fractures in 441 Japanese females with osteoporosis. A total of 979 (858 nonsynonymous and 121 silent) single-nucleotide polymorphisms (SNPs) located in 74 osteoporosis-susceptibility genes wer...

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Detalles Bibliográficos
Autores principales: Zhou, Heying, Mori, Seijiro, Ishizaki, Tatsuro, Takahashi, Atsushi, Matsuda, Koichi, Koretsune, Yukihiro, Minami, Shiro, Higashiyama, Masahiko, Imai, Shinji, Yoshimori, Kozo, Doita, Minoru, Yamada, Akira, Nagayama, Satoshi, Kaneko, Kazuo, Asai, Satoshi, Shiono, Masaki, Kubo, Michiaki, Ito, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440966/
https://www.ncbi.nlm.nih.gov/pubmed/28580384
http://dx.doi.org/10.1016/j.bonr.2016.07.001