Cargando…

Stabilization of 4E-BP1 by PI3K kinase and its involvement in CHK2 phosphorylation in the cellular response to radiation

Objectives: 4E-BP1 is a family member of eIF4E binding proteins (4E-BPs) which act as the suppressors of cap-dependent translation of RNA via competitively associating with cap-bound eIF4E. RNA translation regulation is an important manner to control the cellular responses to a series of stress cond...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Zi-Jian, Luo, Hui-Hui, Shang, Zeng-Fu, Guan, Hua, Xiao, Bei-Bei, Liu, Xiao-Dan, Wang, Yu, Huang, Bo, Zhou, Ping-Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441037/ https://www.ncbi.nlm.nih.gov/pubmed/28539821 http://dx.doi.org/10.7150/ijms.18329

Ejemplares similares

AR phosphorylation and CHK2 kinase activity regulates IR-stabilized AR–CHK2 interaction and prostate cancer survival
por: Ta, Huy Q, et al.
Publicado: (2020)

Interdependent Phosphorylation within the Kinase Domain T-loop Regulates CHK2 Activity
por: Guo, Xin, et al.
Publicado: (2010)

CK1δ Kinase Activity Is Modulated by Chk1-Mediated Phosphorylation
por: Bischof, Joachim, et al.
Publicado: (2013)

Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation
por: Yu, Xinfang, et al.
Publicado: (2020)

Role for casein kinase 1 in the phosphorylation of Claspin on critical residues necessary for the activation of Chk1
por: Meng, Zheng, et al.
Publicado: (2011)

Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer
por: Liu, Kang, et al.
Publicado: (2021)

Chk-mate on resistance to kinase inhibitors
por: Shapiro, Paul
Publicado: (2018)

CHK2 Promotes Metabolic Stress-Induced Autophagy through ULK1 Phosphorylation
por: Guo, Ran, et al.
Publicado: (2022)

The Role of Wild-Type p53 in Cisplatin-Induced Chk2 Phosphorylation and the Inhibition of Platinum Resistance with a Chk2 Inhibitor
por: Liang, Xiaobing, et al.
Publicado: (2011)

7-Ketocholesterol induces ATM/ATR, Chk1/Chk2, PI3K/Akt signalings, cytotoxicity and IL-8 production in endothelial cells
por: Chang, Mei-Chi, et al.
Publicado: (2016)

CHK1 phosphorylates PRIMPOL to promote replication stress tolerance
por: Mehta, Kavi P. M., et al.
Publicado: (2022)

Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation via derepression of Chk1 catalytic activity
por: Walker, M, et al.
Publicado: (2009)

CK2 kinase-mediated PHF8 phosphorylation controls TopBP1 stability to regulate DNA replication
por: Feng, Haihua, et al.
Publicado: (2020)

CK2 kinase-mediated PHF8 phosphorylation controls TopBP1 stability to regulate DNA replication
por: Feng, Haihua, et al.
Publicado: (2021)

Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine
por: Advani, Gahana, et al.
Publicado: (2017)

DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response
por: Lin, Yu-Fen, et al.
Publicado: (2014)

γH2AX and Chk1 phosphorylation as predictive pharmacodynamic biomarkers of Chk1 inhibitor-chemotherapy combination treatments
por: Rawlinson, Rebecca, et al.
Publicado: (2014)

Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function
por: Yu, Ting-Xi, et al.
Publicado: (2011)

Chk1, Chk2, is the amplifier on?
por: Dove, Alan W.
Publicado: (2001)

SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence
por: Gioia, Ubaldo, et al.
Publicado: (2023)

SIRT1 modulates cell cycle progression by regulating CHK2 acetylation−phosphorylation
por: Zhang, Wenyu, et al.
Publicado: (2019)

CHK2 kinase in the DNA damage response and beyond
por: Zannini, Laura, et al.
Publicado: (2014)

Intra-S phase checkpoint kinase Chk1 dissociates replication proteins Treslin and TopBP1 through multiple mechanisms during replication stress
por: Kelly, Rebecca L., et al.
Publicado: (2022)

A novel Chk1-binding peptide that enhances genotoxic sensitivity through the cellular redistribution of nuclear Chk1
por: Kim, Kwang Seok, et al.
Publicado: (2016)

DNA-PKcs activates the Chk2–Brca1 pathway during mitosis to ensure chromosomal stability
por: Shang, Z, et al.
Publicado: (2014)

DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway
por: Shang, Zeng-Fu, et al.
Publicado: (2015)

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G(2)/M DNA Damage Checkpoint
por: van Vugt, Marcel A. T. M., et al.
Publicado: (2010)

RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation
por: Badie, Sophie, et al.
Publicado: (2009)

Phosphoglycerate Mutase Cooperates with Chk1 Kinase to Regulate Glycolysis
por: Mikawa, Takumi, et al.
Publicado: (2020)

The DNA repair component Metnase regulates Chk1 stability
por: Williamson, Elizabeth A, et al.
Publicado: (2014)

Ataxin-3 promotes genome integrity by stabilizing Chk1
por: Tu, Yingfeng, et al.
Publicado: (2017)

Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1
por: Alver, Robert C., et al.
Publicado: (2017)

Phosphorylation-Dependent Interactions between Crb2 and Chk1 Are Essential for DNA Damage Checkpoint
por: Qu, Meng, et al.
Publicado: (2012)

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest
por: Sengupta, Sagar, et al.
Publicado: (2004)

Increases in Mitochondrial DNA Content and 4977-bp Deletion upon ATM/Chk2 Checkpoint Activation in HeLa Cells
por: Niu, Rong, et al.
Publicado: (2012)

VprBP/DCAF1 regulates p53 function and stability through site-specific phosphorylation
por: Ghate, Nikhil Baban, et al.
Publicado: (2023)

Chk1 and Wee1 kinases coordinate DNA replication, chromosome condensation, and anaphase entry
por: Fasulo, Barbara, et al.
Publicado: (2012)

Dominant mutations in CHK1 cause pronuclear fusion failure and zygote arrest that can be rescued by CHK1 inhibitor
por: Zhang, Honghui, et al.
Publicado: (2021)

Polo-Like Kinase 1 phosphorylates and stabilizes KLF4 to promote tumorigenesis in nasopharyngeal carcinoma
por: Mai, Jia, et al.
Publicado: (2019)

Garcinol Alone and in Combination With Cisplatin Affect Cellular Behavior and PI3K/AKT Protein Phosphorylation in Human Ovarian Cancer Cells
por: Zhang, Jie, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_r83p2bi4ufo8hqd9fe1dtqt71f