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LPS-induced systemic inflammation reveals an immunomodulatory role for the prion protein at the blood-brain interface

BACKGROUND: The cellular prion protein (PrP(C)) is an evolutionary conserved protein abundantly expressed not only in the central nervous system but also peripherally including the immune system. A line of Norwegian dairy goats naturally devoid of PrP(C) (PRNP (Ter/Ter)) provides a novel model for s...

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Detalles Bibliográficos
Autores principales:	Salvesen, Ø., Reiten, M. R., Espenes, A., Bakkebø, M. K., Tranulis, M. A., Ersdal, C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441080/ https://www.ncbi.nlm.nih.gov/pubmed/28532450 http://dx.doi.org/10.1186/s12974-017-0879-5

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