Use of the QIAGEN GeneReader NGS system for detection of KRAS mutations, validated by the QIAGEN Therascreen PCR kit and alternative NGS platform

BACKGROUND: The detection of somatic mutations in primary tumors is critical for the understanding of cancer evolution and targeting therapy. Multiple technologies have been developed to enable the detection of such mutations. Next generation sequencing (NGS) is a new platform that is gradually beco...

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Detalles Bibliográficos
Autores principales: Darwanto, Agus, Hein, Anne-Mette, Strauss, Sascha, Kong, Yi, Sheridan, Andrew, Richards, Dan, Lader, Eric, Ngowe, Monika, Pelletier, Timothy, Adams, Danielle, Ricker, Austin, Patel, Nishit, Kühne, Andreas, Hughes, Simon, Shiffman, Dan, Zimmermann, Dirk, te Kaat, Kai, Rothmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441096/
https://www.ncbi.nlm.nih.gov/pubmed/28532404
http://dx.doi.org/10.1186/s12885-017-3328-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441096/
https://www.ncbi.nlm.nih.gov/pubmed/28532404
http://dx.doi.org/10.1186/s12885-017-3328-z

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