Cargando…

Akrinor(TM), a Cafedrine/ Theodrenaline Mixture (20:1), Increases Force of Contraction of Human Atrial Myocardium But Does Not Constrict Internal Mammary Artery In Vitro

Background: Intraoperative hypotension is a common problem and direct or indirect sympathomimetic drugs are frequently needed to stabilize blood pressure. Akrinor(TM) consists of the direct and the indirect sympathomimetic noradrenaline and norephedrine. Both substances are covalently bound to the p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kloth, Benjamin, Pecha, Simon, Moritz, Eileen, Schneeberger, Yvonne, Söhren, Klaus-Dieter, Schwedhelm, Edzard, Reichenspurner, Hermann, Eschenhagen, Thomas, Böger, Rainer H., Christ, Torsten, Stehr, Sebastian N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441130/ https://www.ncbi.nlm.nih.gov/pubmed/28588484 http://dx.doi.org/10.3389/fphar.2017.00272

Ejemplares similares

Phenylephrine versus cafedrine/theodrenaline (Akrinor) for the treatment of spinal anaesthesia-induced maternal hypotension during caesarean section: a retrospective single-centre cohort study
por: Porsche, Raphael, et al.
Publicado: (2022)

Medikamenteninteraktion zwischen Ceftriaxon und Theodrenalin/Cafedrin: Ein Fallbeispiel
por: Werzer, Christina, et al.
Publicado: (2022)

Cafedrine/theodrenaline in anaesthesia: Influencing factors in restoring arterial blood pressure
por: Heller, A. R., et al.
Publicado: (2015)

Cafedrine/Theodrenaline (20:1) Is an Established Alternative for the Management of Arterial Hypotension in Germany—a Review Based on a Systematic Literature Search
por: Bein, Berthold, et al.
Publicado: (2017)

Treatment of intraoperative hypotension with cafedrine/theodrenaline versus ephedrine: A prospective, national, multicenter, non-interventional study—the HYPOTENS trial
por: Eberhart, L., et al.
Publicado: (2020)

Treatment of spinal anaesthesia-induced hypotension with cafedrine/theodrenaline versus ephedrine during caesarean section: Results from HYPOTENS, a national, multicentre, prospective, noninterventional study
por: Kranke, Peter, et al.
Publicado: (2021)

A 20:1 synergetic mixture of cafedrine/theodrenaline accelerates particle transport velocity in murine tracheal epithelium via IP(3) receptor-associated calcium release
por: Schmidt, Götz, et al.
Publicado: (2023)

β(1) Adrenoceptor antagonistic effects of the supposedly selective β(2) adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts
por: Pecha, Simon, et al.
Publicado: (2015)

A fixed 20:1 combination of cafedrine/theodrenaline increases cytosolic Ca(2+) concentration in human tracheal epithelial cells via ryanodine receptor-mediated Ca(2+) release
por: Schmidt, Götz, et al.
Publicado: (2023)

Valvular Cardiomyopathy in Aortic Valve Regurgitation Correlates with Myocardial Fibrosis
por: Petersen, Johannes, et al.
Publicado: (2023)

A New Animal Model for Investigation of Mechanical Unloading in Hypertrophic and Failing Hearts: Combination of Transverse Aortic Constriction and Heterotopic Heart Transplantation
por: Schaefer, Andreas, et al.
Publicado: (2016)

A critical role of retinoic acid concentration for the induction of a fully human-like atrial action potential phenotype in hiPSC-CM
por: Schulz, Carl, et al.
Publicado: (2023)

Diurnal Variation of L-Arginine and the Cardiovascular Risk Markers Asymmetric and Symmetric Dimethylarginine and Homoarginine in Rotating Night Shift Workers and Controls
por: Hannemann, Juliane, et al.
Publicado: (2023)

A study of endothelial function and circulating asymmetric dimethylarginine levels in people with Type 1 diabetes without macrovascular disease or microalbuminuria
por: Sibal, Latika, et al.
Publicado: (2009)

Plasma Nitrate and Incidence of Cardiovascular Disease and All‐Cause Mortality in the Community: The Framingham Offspring Study
por: Maas, Renke, et al.
Publicado: (2017)

Arginine derivatives in atrial fibrillation progression phenotypes
por: Büttner, Petra, et al.
Publicado: (2020)

Correction to: Arginine derivatives in atrial fibrillation progression phenotypes
por: Büttner, Petra, et al.
Publicado: (2021)

Antegrade axillary arterial perfusion in 3D endoscopic minimally-invasive mitral valve surgery
por: Petersen, Johannes, et al.
Publicado: (2022)

Characterization of Transverse Aortic Constriction in Mice Based on the Specific Recruitment of Leukocytes to the Hypertrophic Myocardium and the Aorta Ascendens
por: Kleiner, Jan Lukas, et al.
Publicado: (2021)

Effect of ranolazine on plasma arginine derivatives and urinary isoprostane 8-iso-PGF(2α) in patients with myocardial infarction in the randomized RIMINI-Trial
por: Schwemer, Tjark F., et al.
Publicado: (2019)

Association of Asymmetric and Symmetric Dimethylarginine with Inflammation in the Population-Based Study of Health in Pomerania
por: Winkler, Martin Sebastian, et al.
Publicado: (2023)

Population kinetics of homoarginine and optimized supplementation for cardiovascular risk reduction
por: Kleist, Christine J., et al.
Publicado: (2022)

Developmental dynamics of homoarginine, ADMA and SDMA plasma levels from birth to adolescence
por: Baach, Florence, et al.
Publicado: (2023)

Dynamics of Vascular Protective and Immune Supportive Sphingosine-1-Phosphate During Cardiac Surgery
por: Greiwe, Gillis, et al.
Publicado: (2021)

Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density
por: Lemoine, Marc D., et al.
Publicado: (2017)

Symmetrical (SDMA) and asymmetrical dimethylarginine (ADMA) in sepsis: high plasma levels as combined risk markers for sepsis survival
por: Winkler, Martin Sebastian, et al.
Publicado: (2018)

Association of Lower Plasma Homoarginine Concentrations with Greater Risk of All-Cause Mortality in the Community: The Framingham Offspring Study
por: Schwedhelm, Edzard, et al.
Publicado: (2020)

Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model
por: Pecha, Simon, et al.
Publicado: (2019)

Association of Asymmetric Dimethylarginine and Diastolic Dysfunction in Patients with Hypertrophic Cardiomyopathy
por: Cordts, Kathrin, et al.
Publicado: (2019)

TAVI for Pure Non-calcified Aortic Regurgitation Using a Self-Expandable Transcatheter Heart Valve
por: Schneeberger, Yvonne, et al.
Publicado: (2022)

Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes
por: Kloth, Benjamin, et al.
Publicado: (2022)

Blinded Contractility Analysis in hiPSC-Cardiomyocytes in Engineered Heart Tissue Format: Comparison With Human Atrial Trabeculae
por: Mannhardt, Ingra, et al.
Publicado: (2017)

L-Arginine and SDMA Serum Concentrations Are Associated with Subclinical Atherosclerosis in the Study of Health in Pomerania (SHIP)
por: Bahls, Martin, et al.
Publicado: (2015)

Asymmetric Dimethylarginine at Sea Level Is a Predictive Marker of Hypoxic Pulmonary Arterial Hypertension at High Altitude
por: Siques, Patricia, et al.
Publicado: (2019)

Arginine:Glycine Amidinotransferase Is Essential for Creatine Supply in Mice During Chronic Hypoxia
por: Hannemann, Juliane, et al.
Publicado: (2021)

Elevated serum SDMA and ADMA at hospital admission predict in-hospital mortality of COVID-19 patients
por: Hannemann, Juliane, et al.
Publicado: (2021)

Markers of nitric oxide are associated with sepsis severity: an observational study
por: Winkler, Martin Sebastian, et al.
Publicado: (2017)

Rare Presentation of Sinus of Valsalva Aneurysm Treated by Aortic Valve Reimplantation Technique
por: Petersen, Johannes, et al.
Publicado: (2022)

Proteomic Analysis in Valvular Cardiomyopathy: Aortic Regurgitation vs. Aortic Stenosis
por: Holst, Theresa, et al.
Publicado: (2023)

Incidence of All-Cause and Cardiovascular Mortality Predicted by Symmetric Dimethylarginine in the Population-Based Study of Health in Pomerania
por: Schwedhelm, Edzard, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_e8i15ptjju3fmpnucoapd80u3q