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Profile of Lymphadenopathy: An Institutional Based Cytomorphological Study

INTRODUCTION: Lymphadenopathy is one of the most common clinical presentations of patients attending the outdoor department of a hospital. Lymph node aspiration is of great value for the diagnosis of lymphadenitis, lymphomas, and metastatic carcinoma. MATERIALS AND METHODS: In this study, we have re...

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Autores principales: Malhotra, Aneeta Singh, Lahori, Mega, Nigam, Arti, Khajuria, Arvind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441255/
https://www.ncbi.nlm.nih.gov/pubmed/28584739
http://dx.doi.org/10.4103/2229-516X.205812
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author Malhotra, Aneeta Singh
Lahori, Mega
Nigam, Arti
Khajuria, Arvind
author_facet Malhotra, Aneeta Singh
Lahori, Mega
Nigam, Arti
Khajuria, Arvind
author_sort Malhotra, Aneeta Singh
collection PubMed
description INTRODUCTION: Lymphadenopathy is one of the most common clinical presentations of patients attending the outdoor department of a hospital. Lymph node aspiration is of great value for the diagnosis of lymphadenitis, lymphomas, and metastatic carcinoma. MATERIALS AND METHODS: In this study, we have reported the pattern of cytological diagnosis on fine-needle aspiration cytology (FNAC) of lymphadenopathy cases in Jammu region of Jammu and Kashmir state of India. The mean age of all the patients in this study was 21.67 years. The most common site of lymphadenopathy was cervical region (71.79%) followed by axillary region (11.11%). RESULTS: Tubercular lymphadenitis (44.02%) was the single most common cause of lymphadenopathy followed by reactive lymphadenitis (42.64%), metastatic lesions (9.40%), and malignant lymphoma (4.70%). The sensitivity of 94.49%, positive predictive value of 96.26%, and diagnostic accuracy of 91.15% was achieved in our study. CONCLUSION: This study highlights the role of FNAC as a simple, inexpensive, relatively painless, rapid, repeatable, and reliable method of investigation for lymphadenopathy, especially in outpatient departments, peripheral hospitals, and dispensaries.
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spelling pubmed-54412552017-06-05 Profile of Lymphadenopathy: An Institutional Based Cytomorphological Study Malhotra, Aneeta Singh Lahori, Mega Nigam, Arti Khajuria, Arvind Int J Appl Basic Med Res Original Article INTRODUCTION: Lymphadenopathy is one of the most common clinical presentations of patients attending the outdoor department of a hospital. Lymph node aspiration is of great value for the diagnosis of lymphadenitis, lymphomas, and metastatic carcinoma. MATERIALS AND METHODS: In this study, we have reported the pattern of cytological diagnosis on fine-needle aspiration cytology (FNAC) of lymphadenopathy cases in Jammu region of Jammu and Kashmir state of India. The mean age of all the patients in this study was 21.67 years. The most common site of lymphadenopathy was cervical region (71.79%) followed by axillary region (11.11%). RESULTS: Tubercular lymphadenitis (44.02%) was the single most common cause of lymphadenopathy followed by reactive lymphadenitis (42.64%), metastatic lesions (9.40%), and malignant lymphoma (4.70%). The sensitivity of 94.49%, positive predictive value of 96.26%, and diagnostic accuracy of 91.15% was achieved in our study. CONCLUSION: This study highlights the role of FNAC as a simple, inexpensive, relatively painless, rapid, repeatable, and reliable method of investigation for lymphadenopathy, especially in outpatient departments, peripheral hospitals, and dispensaries. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5441255/ /pubmed/28584739 http://dx.doi.org/10.4103/2229-516X.205812 Text en Copyright: © 2017 International Journal of Applied and Basic Medical Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Malhotra, Aneeta Singh
Lahori, Mega
Nigam, Arti
Khajuria, Arvind
Profile of Lymphadenopathy: An Institutional Based Cytomorphological Study
title Profile of Lymphadenopathy: An Institutional Based Cytomorphological Study
title_full Profile of Lymphadenopathy: An Institutional Based Cytomorphological Study
title_fullStr Profile of Lymphadenopathy: An Institutional Based Cytomorphological Study
title_full_unstemmed Profile of Lymphadenopathy: An Institutional Based Cytomorphological Study
title_short Profile of Lymphadenopathy: An Institutional Based Cytomorphological Study
title_sort profile of lymphadenopathy: an institutional based cytomorphological study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441255/
https://www.ncbi.nlm.nih.gov/pubmed/28584739
http://dx.doi.org/10.4103/2229-516X.205812
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