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A Blind Test of Computational Technique for Predicting the Likelihood of Peptide Sequences to Cyclize
[Image: see text] An in silico computational technique for predicting peptide sequences that can be cyclized by cyanobactin macrocyclases, e.g., PatG(mac), is reported. We demonstrate that the propensity for PatG(mac)-mediated cyclization correlates strongly with the free energy of the so-called pre...
Autores principales: | Booth, Jonathan, Alexandru-Crivac, Christina-Nicoleta, Rickaby, Kirstie A., Nneoyiegbe, Ada F., Umeobika, Ugochukwu, McEwan, Andrew R., Trembleau, Laurent, Jaspars, Marcel, Houssen, Wael E., Shalashilin, Dmitrii V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2017
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441752/ https://www.ncbi.nlm.nih.gov/pubmed/28475844 http://dx.doi.org/10.1021/acs.jpclett.7b00848 |
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