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The relationship between chain connectivity and domain stability in the equilibrium and kinetic folding mechanisms of dihydrofolate reductase from E.coli

The role of domains in defining the equilibrium and kinetic folding properties of dihydrofolate reductase (DHFR) from Escherichia coli was probed by examining the thermodynamic and kinetic properties of a set of variants in which the chain connectivity in the discontinuous loop domain (DLD) and the...

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Detalles Bibliográficos
Autores principales: Svensson, Anna-Karin E., Zitzewitz, Jill A., Matthews, C.Robert, Smith, Virginia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441858/
https://www.ncbi.nlm.nih.gov/pubmed/16452118
http://dx.doi.org/10.1093/protein/gzj017

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