Loss of Ptpn11 (Shp2) drives satellite cells into quiescence

The equilibrium between proliferation and quiescence of myogenic progenitor and stem cells is tightly regulated to ensure appropriate skeletal muscle growth and repair. The non-receptor tyrosine phosphatase Ptpn11 (Shp2) is an important transducer of growth factor and cytokine signals. Here we combi...

Descripción completa

Detalles Bibliográficos
Autores principales: Griger, Joscha, Schneider, Robin, Lahmann, Ines, Schöwel, Verena, Keller, Charles, Spuler, Simone, Nazare, Marc, Birchmeier, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441871/
https://www.ncbi.nlm.nih.gov/pubmed/28463680
http://dx.doi.org/10.7554/eLife.21552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441871/
https://www.ncbi.nlm.nih.gov/pubmed/28463680
http://dx.doi.org/10.7554/eLife.21552

Ejemplares similares