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The molecular determinants for distinguishing between ubiquitin and NEDD8 by USP2

Ubiquitin (Ub) shares the highest sequence identity with neuronal-precursor-cell-expressed developmentally downregulated protein-8 (NEDD8) in the Ub-like protein family. However, different enzyme systems are precisely employed for targeting Ub and NEDD8 to specific substrates. The molecular determin...

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Detalles Bibliográficos
Autores principales: Shin, Yung-Cheng, Chen, Jou-Han, Chang, Shih-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442100/
https://www.ncbi.nlm.nih.gov/pubmed/28536428
http://dx.doi.org/10.1038/s41598-017-02322-x