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Secreted Frizzled-related protein 4 (sFRP4) chemo-sensitizes cancer stem cells derived from human breast, prostate, and ovary tumor cell lines

This study investigated molecular signals essential to sustain cancer stem cells (CSCs) and assessed their activity in the presence of secreted frizzled-related protein 4 (sFRP4) alone or in combination with chemotherapeutic drugs. SFRP4 is a known Wnt antagonist, and is also pro-apoptotic and anti-...

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Detalles Bibliográficos
Autores principales:	Deshmukh, A., Kumar, S., Arfuso, F., Newsholme, P., Dharmarajan, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442130/ https://www.ncbi.nlm.nih.gov/pubmed/28536422 http://dx.doi.org/10.1038/s41598-017-02256-4

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