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Claudin Loss-of-Function Disrupts Tight Junctions and Impairs Amelogenesis

Claudins are a family of proteins that forms paracellular barriers and pores determining tight junctions (TJ) permeability. Claudin-16 and -19 are pore forming TJ proteins allowing calcium and magnesium reabsorption in the thick ascending limb of Henle's loop (TAL). Loss-of-function mutations i...

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Detalles Bibliográficos
Autores principales:	Bardet, Claire, Ribes, Sandy, Wu, Yong, Diallo, Mamadou Tidiane, Salmon, Benjamin, Breiderhoff, Tilman, Houillier, Pascal, Müller, Dominik, Chaussain, Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442167/ https://www.ncbi.nlm.nih.gov/pubmed/28596736 http://dx.doi.org/10.3389/fphys.2017.00326

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