Time-Resolved Tracking of Mutations Reveals Diverse Allele Dynamics during Escherichia coli Antimicrobial Adaptive Evolution to Single Drugs and Drug Pairs

Understanding the evolutionary processes that lead to antibiotic resistance can help to achieve better treatment strategies. Yet, little is known about the dynamics of the resistance alleles during adaptation. Here, we use population sequencing to monitor genetic changes in putative resistance loci...

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Detalles Bibliográficos
Autores principales: Hickman, Rachel A., Munck, Christian, Sommer, Morten O. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442168/
https://www.ncbi.nlm.nih.gov/pubmed/28596757
http://dx.doi.org/10.3389/fmicb.2017.00893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442168/
https://www.ncbi.nlm.nih.gov/pubmed/28596757
http://dx.doi.org/10.3389/fmicb.2017.00893

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