Cargando…
Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca(2+) Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK
Several new therapeutic options emerged recently to treat metastatic melanoma; however, the high frequency of intrinsic and acquired resistance among patients shows a need for new therapeutic options. Previously, we identified the plasma membrane Ca(2+) ATPase 4b (PMCA4b) as a metastasis suppressor...
Autores principales: | Hegedüs, Luca, Padányi, Rita, Molnár, Judit, Pászty, Katalin, Varga, Karolina, Kenessey, István, Sárközy, Eszter, Wolf, Matthias, Grusch, Michael, Hegyi, Zoltán, Homolya, László, Aigner, Clemens, Garay, Tamás, Hegedüs, Balázs, Tímár, József, Kállay, Enikö, Enyedi, Ágnes |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442207/ https://www.ncbi.nlm.nih.gov/pubmed/28596940 http://dx.doi.org/10.3389/fonc.2017.00095 |
Ejemplares similares
-
Expression of calcium pumps is differentially regulated by histone deacetylase inhibitors and estrogen receptor alpha in breast cancer cells
por: Varga, Karolina, et al.
Publicado: (2018) -
P38 MAPK Promotes Migration and Metastatic Activity of BRAF Mutant Melanoma Cells by Inducing Degradation of PMCA4b
por: Naffa, Randa, et al.
Publicado: (2020) -
The Plasma Membrane Ca(2+) Pump PMCA4b Regulates Melanoma Cell Migration through Remodeling of the Actin Cytoskeleton
por: Naffa, Randa, et al.
Publicado: (2021) -
The Antitumor Effect of Lipophilic Bisphosphonate BPH1222 in Melanoma Models: The Role of the PI3K/Akt Pathway and the Small G Protein Rheb
por: Rittler, Dominika, et al.
Publicado: (2019) -
Horizontal Combination of MEK and PI3K/mTOR Inhibition in BRAF Mutant Tumor Cells with or without Concomitant PI3K Pathway Mutations
por: Rittler, Dominika, et al.
Publicado: (2020)